# HERCULES: Exposome Research Center

> **NIH NIH P30** · EMORY UNIVERSITY · 2024 · $290,847

## Abstract

HERCULES: ENVIRONMENTAL HEALTH DATA SCIENCE CORE – SUMMARY 
Partnering with HERCULES Cores that define and apply (Community Engagement Core, CEC), innovate (Pilot 
Project Program, PPP), operationalize (Integrated Health Sciences Facility Core (IHSFC), and coordinate and 
evaluate (Administrative Core), the Environmental Health Data Sciences Core (EHDSC) functions to enable 
and interpret translational research on the exposome. Specifically, the EHDSC will: 1) Develop and support 
data pipelines linking the wide range of HERCULES Members’ datasets to projects large and small (Aim 1); 2) 
Advance expanded and customized data management and analysis plans, implement novel analytic 
approaches, and expand the HERCULES data and analytic infrastructure (Aim 2); and 3) Provide in-depth 
introductions and training sessions for HERCULES Members and partners focusing on data science principles, 
statistical and machine learning design and analysis, and analytic modeling tools of computational systems 
biology (Aim 3). All three functions are essential to translate exposome-related data of different measurement 
types taken from different places at different times into informative, interpretable, and communicable results for 
community members, stakeholders, researchers, and policy makers. Building on a connected collaborative 
network between our experienced data science professionals and HERCULES Members and community 
partners, the EHDSC will 1) provide the Administrative Core with insight into existing and emerging trends in 
data management and analysis from inside and outside the HERCULES community in order to assure training 
of all Members and support for new and early career investigators; 2) collaborate directly with the CEC in 
working with HERCULES community partners to identify relevant existing data sources, partnerships with 
HERCULES Members, and/or support citizen science efforts to provide data collection, data management, and 
data communication plans; 3) partner with the IHFSC to link health outcomes and exposure measurements in 
innovative ways quantifying, operationalizing, and interpreting exposome data within translational 
environmental health research; 4) accelerate the innovative research of the Pilot Program by providing 
needed support across a range of data science needs. Taken together, the EHDSC provides clear 
connections to all elements of HERCULES and complements the Administrative Core, the CEC, the Pilot 
Program, and the IHSFC through close collaboration in our overall mission of learning how the exposome 
affects health and community well-being and using that knowledge to improve human health.

## Key facts

- **NIH application ID:** 10814985
- **Project number:** 5P30ES019776-12
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** Lance A Waller
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $290,847
- **Award type:** 5
- **Project period:** 2013-05-21 → 2027-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10814985

## Citation

> US National Institutes of Health, RePORTER application 10814985, HERCULES: Exposome Research Center (5P30ES019776-12). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10814985. Licensed CC0.

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