ABSTRACT The Administrative Core will provide administrative support to PPG scientists with the goals of coordinating all components of the program, enhancing interactions between the components of the PPG, optimizing the efficiency of the operation, establishing internal and external vehicles for communication, and providing accounting support consistent with federal and institutional policies and procedures. The Administrative Core will be led by David Schwartz, MD who will coordinate interactions with the Scientific Projects and Research Cores, institutions (University of Colorado, National Jewish Health, and University of North Carolina), Internal and External Advisory Committees, and NHLBI. Ivana Yang, PhD will serve as Associate Director of the Administrative Core and she will assume responsibilities for organizing the Scientific Project (every 2 weeks), Research Core (every 2 weeks), and Program (monthly) meetings and will also be responsible of the outside scientific speaker program and the public component of the annual PPG retreat. The Administrative Core will play a central role to support the organizational structure, and promote and coordinate interdisciplinary research in PPG. The objectives of the Administrative Core include: Support the administrative needs of PPG scientists and provide fiscal management Coordinate and integrate internal components of the PPG Coordinate and integrate the PPG with external stakeholders Provide overall leadership for the PPG