# NICHD Cooperative Multicenter Neonatal Research Network

> **NIH NIH UG1** · UNIVERSITY OF IOWA · 2024 · $338,534

## Abstract

Project Summary
The University of Iowa submits this renewal application for continued participation in the NICHD
Neonatal Research Network (RFA-HD-23-002). We seek to continue to support the mission of the NRN
to improve healthcare and outcomes for newborns, seeking solutions to increase survival without
neurodevelopmental impairment or chronic illness for premature and critically ill newborn infants. We
have several strengths that will advance the collaborative work of the NRN.
 1. Our NICU is a world leader in the care of periviable infants, born at 22 and 23 weeks’ gestation.
The survival rate of this population at the University of Iowa is the best in the United States, and the
majority of these survivors are free of neurodevelopmental impairment. We bring expertise to inform
research design as well as a relatively large periviable population available to participate in NRN
studies. Our mortality for extremely low birth weight infants is perennially among the lowest in the NRN.
 2. We have a strong tradition and culture of clinical research in infants. Our clinical research
infrastructure in the NICU has a decades-long track record of successful participation in multicenter
studies and contributions to important neonatal study findings.
 3. Our NICU is the leading US center in the emerging neonatal subspecialty of neonatal
hemodynamics. Our Hemodynamics group has developed the study methods and echocardiographic
measurement standards for this modality and are global experts in its use both clinically and in
physiologic and interventional research. That expertise can be harnessed in the NRN to pursue novel
study designs.
 4. As the only academic medical center in a largely rural state with an economy based in agriculture,
we represent a population that is not otherwise well represented in the NICHD Network. Our partner
site at Sanford Health in Sioux Falls, SD further enhances this diversity with the addition of a Native
American population to our combined rural population. If the results of Network studies are to be
generalized to patients throughout the country, this large area of the country should be represented.
The University of Iowa Network center represents this region and population.
 5. We have contributed significantly to the NRN’s work through the last 7 years. We have been
among the highest enrolling sites in several studies despite our relatively low population, and we have
had excellent follow-up rates for infants both in trials and in the Follow-up observational study.

## Key facts

- **NIH application ID:** 10817948
- **Project number:** 5UG1HD053109-19
- **Recipient organization:** UNIVERSITY OF IOWA
- **Principal Investigator:** Tarah Trinity Colaizy
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $338,534
- **Award type:** 5
- **Project period:** 2006-04-05 → 2030-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10817948

## Citation

> US National Institutes of Health, RePORTER application 10817948, NICHD Cooperative Multicenter Neonatal Research Network (5UG1HD053109-19). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10817948. Licensed CC0.

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