# Columbia University Maternal-Fetal Medicine Units Network Clinical Center

> **NIH NIH UG1** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $359,801

## Abstract

Abstract/Project Summary
The Columbia Center has a 20-year track record of excellence within the Maternal Fetal Medicine Units
(MFMU) Network and collaborating in large multi-site clinical trials and longitudinal studies in pregnant and
lactating people. During the last current cycle of the MFMU, the Columbia Center ranked near the top in
recruitment for every study. The Columbia Center will be composed of Columbia University and 3 satellite
sites including: Christiana Care Health System, Saint Peter's University Hospital, and Yale New Haven
Hospital which operate under a common administrative and oversight structure. Together, these 4 large-
volume delivery centers provide access to 23,500 patients annually with diversity in race and ethnicity (24%
Black, 24% Hispanic, 9% Asian), socioeconomic status, and access to underserved communities. As a result
of our strong presence of MFM, Neonatology and subspecialty care and facilities at each site, 40% of our
overall delivery population is high-risk. Network protocols will be conducted in a coordinated, rigorous and safe
manner by our Center's highly qualified investigators, staff, dedicated MFMU facilities and culture of clinical
research being part of clinical care. The Columbia Center has the experience and expertise to collaboratively
conduct multi-site randomized trials and large observational studies with timely recruitment, community-
engaged enrollment of eligible participants from diverse patient populations with excellent retention and
rigorous data collection to contribute to results which will promote advances in obstetric practice. The
Columbia Center has numerous strengths and will provide multidisciplinary expertise on obstetrics,
neonatology, obstetric pharmacology, infant neurodevelopment and lactation clinical practice to address
maternal death and complications related to pregnancy, labor, and post-partum recovery; to reduce
prematurity, low-birth weight, infant death, and infant complications and expand the evidence base about the
safety and efficacy of medications used during pregnancy and lactation. Our Center has state-of-the-art
scientific capabilities for Network research including imaging, genomics, proteomics, placental function
assessment, innovative trial design and analyses, and specialized support of clinical trials. Lastly, our goal is
to provide rigorous data and biospecimen collection to share as a resource for other investigators to advance
evidence-based obstetric practice.

## Key facts

- **NIH application ID:** 10818498
- **Project number:** 5UG1HD040485-25
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Uma Reddy
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $359,801
- **Award type:** 5
- **Project period:** 2001-04-01 → 2030-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10818498

## Citation

> US National Institutes of Health, RePORTER application 10818498, Columbia University Maternal-Fetal Medicine Units Network Clinical Center (5UG1HD040485-25). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10818498. Licensed CC0.

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