PROJECT SUMMARY- ADMINISTRATIVE CORE Cornell University will be the lead institution on the Cornell ME/CFS Collaborative Research Center (CCRC), which constitutes a multi-institutional effort involving key personnel from four Colleges within Cornell University in Ithaca, the Hospital for Special Surgery in New York City, the Susan Levine Clinic, and Florida Atlantic University. The Administrative Core team will be responsible for the organization and synergy of project personnel at the multiple sites and will be responsible for effective oversight and management of all project operations, both scientific and administrative. The Center will be managed by an experienced Center Administrator, who will oversee the day-to-day operations including subcontracts with our partner institutions, scientific coordination with the Research Core and with the data management and coordinating center (DMCC) and other ME/CFS CRCs, as well as administrative, budgetary, scientific and any other post-award aspects of the Center operations. In addition, the project team will be guided by several committees, an internal Executive Committee and a Patient/Advocate/Caregiver Advisory Committee (PAC). The overall goal of the Administrative Core of this Center is to ensure effective administrative and organizational capabilities, both within our Center, and within the broader ME/CFS CRC network, and to operate a successful outreach program to bring the importance and current knowledge of ME/CFS to a wider audience. The Administrative Core will work to create synergy among the research projects, the Research Core and the Outreach components of the Center to create a seamless, well- functioning unit.