# CSHL Neuroscience of Addiction Course (2024-2027)

> **NIH NIH R13** · COLD SPRING HARBOR LABORATORY · 2024 · $40,000

## Abstract

Cold Spring Harbor Laboratory Lecture Course
NEUROSCIENCE OF ADDICTION (2024-2027)
Abstract
Drug addiction is among the most prevalent and costly neuropsychiatric disorders faced by our nation. Acute
and repeated exposure to drugs produces neuroadaptation and long-term memories of the experience, but the
circuitry, cellular and molecular adaptations underlying it are only partially understood. There is a need for
increased research in this area that bridges basic and clinical perspectives. The primary objective of the
proposed lecture-and-discussion course is to provide an intensive discussion of the fundamentals, state-of-the-
art advances and major gaps in the neurobiology of drug addiction. Targeted to both new and experienced
investigators, the course will combine formal presentations and informal discussions to convey the merits and
excitement of behavioral, circuitry, cellular and molecular approaches to drug addiction research both at the
preclinical and clinical levels. A range of disciplines and topics will be represented, including noninvasive brain
imaging to identify drug targets and adaptive processes; neuroadaptive processes at the molecular and cellular
level, neural circuits/networks and their modulation, the relevance of genotype and genotype/environmental
interactions to susceptibility and drug response; tolerance and adaptation at the cellular level and approaches
to exploiting the daunting volume generated by neuroinformatics. The course will provide an integrated view of
current and novel research on neuroadaptive responses to addictive drugs. The course will foster discussion
on career development, ethical considerations, collaboration, and integration, as well as provide critical
information needed to construct models of addiction as a disease and identify novel targets for treatments.
Beyond the plane of scientific endeavor, the information is vital for formulating public policy and for
enlightening the public on the neurobiological consequences of drug use and addiction. The course is
designed to generate awareness and interest in multiple levels of analysis, open conduits for collaborations
and present novel routes to investigating the neurobiology of addictive drugs. The course makes every effort to
include a diverse group of participants, being particularly mindful of the inclusion of women, US minorities and
a good balance of national and international scientists. The course has an excellent track record of training and
retaining young scientists in neurobiological and specifically in addiction research. Finally, CSHL has
developed mechanisms for dissemination of the scientific presentations to a broader audience through the use
of open access video archives of the lectures available on Youtube and similar sites.

## Key facts

- **NIH application ID:** 10827538
- **Project number:** 2R13DA019791-14
- **Recipient organization:** COLD SPRING HARBOR LABORATORY
- **Principal Investigator:** DAVID J. STEWART
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $40,000
- **Award type:** 2
- **Project period:** 2005-07-01 → 2028-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10827538

## Citation

> US National Institutes of Health, RePORTER application 10827538, CSHL Neuroscience of Addiction Course (2024-2027) (2R13DA019791-14). Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/grant/nih/10827538. Licensed CC0.

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