Overall Network Organization and Management Plan – Abstract In this proposal the NV INBRE will continue to pursue the goals of enhancing biomedical research infrastructure, research competitiveness, training and workforce development throughout the state of Nevada. The specific focus of this research is Cell Growth and Differentiation. Every two- and four-year teaching college and university in Nevada participates in this program as either Lead (University of Nevada, Reno), Partner (University of Nevada, Las Vegas and Desert Research Institute) or Outreach Institution. The Developmental Research Project Program (DRPP) will provide biomedical research opportunities designed to develop research scientists and provide students research experiences at both Partner and Outreach Institutions. Structured mentorship and collaboration programs enhance DRPP success. The Administrative Core will provide operational support and will coordinate undergraduate research programs at Outreach and Partner Institutions. Research faculty and students will present their research at the NV INBRE Annual Meeting as well as at scientific meetings held at two different Outreach Institutions. The Data Science Core will provide statewide research resources in bioinformatics, proteomics, genomics, cloud computing, and data storage and processing and will provide workshops, education, and training to Outreach and Partner Institutions. Nevada is a majority minority state and NV INBRE ensures that underrepresented populations are proportionally represented in our Administrative Core and in all of our programs. Through these programs, NV INBRE will continue to improve Nevada’s healthcare and biomedical workforce, infrastructure, and base.