THE HARC CENTER: HIV ACCESSORY AND REGULATORY COMPLEXES ADMINISTRATIVE CORE Lead: Nevan Krogan; Co-Lead: Lorena Zuliani-Alvarez SUMMARY The mission of the Administrative Core is to support and promote the scientific and collaborative goals of the HARC Center. The Core will provide leadership that ensures strong oversight and representation of all stakeholders in decisions, facilitate the integration of research projects, and connect the HARC Center to the broader NIAID Centers for HIV Structural Biology. Day-to-day activities will be coordinated by a team co-lead by the HARC Center Director (Dr. Nevan Krogan), who has extensive experience leading and managing large research centers, and the Administrative Core Co-Lead (Dr. Lorena Zuliani-Alvarez). They will be supported by the UCSF Quantitative Biosciences Institute (QBI) administrative team. Evaluation of progress toward the Center’s goals as well as budgeting and long-term planning of center activities will be performed by the HARC Center Executive Committee (EC), consisting of the Director, Project Leads (Drs. Gross, Marson, and Frankel) and the co-Lead of the Administrative Core (Zuliani-Alvarez). As a first task of the Executive Committee, a Scientific Advisory Board (SAB) will be formed to review the Center’s progress and future plans. The Administrative Core will organize and manage a number of regularly scheduled meetings for the EC, the entire HARC Center, and the wider HIV research community to facilitate communication amongst members and provide ample opportunities to discuss overall research directions and specific experimental concerns. In collaboration with the Developmental Core, the Administrative Core will maintain the HARC Center website (harc.ucsf.edu) and shared file servers. To provide formal site review and involvement with NIAID staff, the Core will organize an annual SAB Meeting, in which the PIs and key personnel will meet with the SAB and NIAID program staff to review the Center’s activities. The HARC Center’s outreach activities and efforts to increase diversity, equity, and inclusion (DEI) will encompass workshops, podcasts, and internships for URM students and will be supported by the QBI Media & Events team.