# Chemical Analysis & Detection

> **NIH NIH P30** · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $132,673

## Abstract

CHEMICAL ANALYSIS AND DETECTION FACILITY CORE – ABSTRACT
The diverse research performed by Center investigators requires the ability to identify and measure a wide array
of contaminants in the environment and in biological samples. The Chemical Analysis and Detection (CAD)
Facility Core addresses this need through the development of new methods for detection and measurement of
small molecules and metals present in various matrices. As the number and quantities of new and emerging
environmental contaminants increases, CAD strives to develop high throughput analytical methods that can
measure 100 or more analytes in a single assay. The Core staff includes five PhD chemical analysts who prepare
and analyze samples, maintain cutting edge analytical capabilities, and develop methods as needed to respond
to new environmental challenges. Most analytical measurements are performed using the Core’s extensive
capabilities in mass spectrometry, which includes gas chromatography/mass spectrometry (GC/MS) and liquid
chromatography/mass spectrometry (LC/MS) methods for identification and quantitation of organic
contaminants, as well as inductively coupled plasma mass spectrometry (ICP/MS) for quantification of metals.
The Facility Core staff are highly experienced researchers who work with investigators on experimental design,
appropriate sample collection methods, customization of existing assays, and development of unique assays.
Following analyses, CAD assists with data interpretation and review of quality assurance and quality control.
CAD works closely with the CEED Translational Research Support Core, the Community Engagement Core and
the Research Cores to ensure that samples are prepared appropriately for analysis. CAD also offers training in
mass spectrometry to CEED members, students and postdocs, enabling them to run their own assays with
supervision from Core staff. During the current grant period, the Core has analyzed over 16,000 samples from
26 different CEED investigators. During the next grant period, CAD will expand and refine existing methods in
multiclass targeted analysis (e.g., endocrine disruptors, PFAS). CAD is also designing new methods based on
non-targeted LC/MS analysis for identification of contaminants in environmental samples, as well exposomic
approaches for hazard assessment. Additionally, CAD is developing laser ablation ICP/MS methods for use in
spatial and temporal quantitation of metals (e.g., teeth, tissue samples, and hair). As part of CAD’s role in rapid
response to disasters, core researchers also evaluate, optimize, and validate methods for the use of field ready
sensors and passive samplers. The Core’s combination of expertise, experience, and access to sophisticated
instrumentation provides critical support for CEED research projects that require either routine or state-of-the-
art science capabilities for measuring small molecules and metal contaminants that adversely impact human
health. CAD’s extensive analytic too...

## Key facts

- **NIH application ID:** 10830090
- **Project number:** 2P30ES005022-37
- **Recipient organization:** RUTGERS BIOMEDICAL AND HEALTH SCIENCES
- **Principal Investigator:** BRIAN T BUCKLEY
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $132,673
- **Award type:** 2
- **Project period:** 1997-04-01 → 2029-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10830090

## Citation

> US National Institutes of Health, RePORTER application 10830090, Chemical Analysis & Detection (2P30ES005022-37). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10830090. Licensed CC0.

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