# Pilot Effectiveness Trial of THRIVE in Crisis Stabilization Centers: Promoting Connection, Recovery, and Treatment Linkage after Suicide Crisis

> **NIH NIH R34** · UNIVERSITY OF ROCHESTER · 2024 · $279,613

## Abstract

Abstract
The US is poised for growth and investment in our mental health crisis system, with a national phone/text
line launching, accompanied by new funding for crisis services. More than 600 Crisis Stabilization Centers
(CSCs) across the US provide suicidal clients with a more comfortable and less costly alternative to
Emergency Department (ED) care. In light of rising demand, there is an urgent need for feasible,
effective, interpersonal, recovery-oriented interventions. This study adapts and tests a novel
intervention for delivery prior to and after discharge from CSCs. THRIVE uses the Interpersonal Theory of
Suicide as a framework to bolster social connectedness and counter perceived burdensomeness.
Preliminary data shows promising results. However, CSC workflows and culture require context-specific
adaptation. This study leverages the Model for Adaptation Design and Impact to adapt THRIVE for CSCs,
test feasibility, acceptability, and appropriateness, and conduct a pilot RCT in two CSCs. The CSC-adapted
intervention addresses interpersonal drivers of suicide risk and bolsters safety, recovery, and community
linkage through: (a) a `belonging and giving' group during CSC stay, (b) recovery coaching calls for 4 weeks
post-discharge, and (c) an optional phone app that provides reinforcement and resources for connection.
The pilot will compare THRIVE + Discharge/Safety Planning (D/SP) to D/SP alone, examining the degree
to which THRIVE engages the targeted mechanisms of change at one- and three-months post-discharge.
Aim 1. Adapt THRIVE and complete CSC-specific manual using MADI.
Aim 2. Test feasibility, acceptability, appropriateness of THRIVE for CSCs.
 CSC Guests (n = 20). 75% of guests will participate in a THRIVE group and at least one follow-up
 session within one month of discharge. Ratings of acceptability and satisfaction will be ≧ 75%.
 CSC Staff (n = 4). Fidelity ratings of audio recordings of group and coaching calls with be at least
 ≧ 75% for all staff who deliver THRIVE.
 CSC Administrators will rate acceptability and appropriateness of THRIVE for CSCs as ≧ 75%.
Aim 3. Conduct a randomized pilot effectiveness trial (n = 162) to assess the effect of THRIVE on
treatment initiation and on key interpersonal drivers of suicide – belongingness and burdensomeness. We
hypothesize that CSC guests who receive THRIVE + D/SP vs. D/SP alone will have:
 H1: Higher rates of treatment initiation at 1 month and 3 months from CSC discharge.
 H2. Increased belongingness and decreased burdensomeness at 1 and 3 months after discharge.
We will explore the effect of the intervention on treatment engagement, acute care psychiatric
readmissions, and suicidal ideation and suicidal behavior over 3-month follow-up. At the end of the study,
THRIVE for CSCs will be ready to test in an effectiveness trial for preventing suicidal behavior.

## Key facts

- **NIH application ID:** 10830386
- **Project number:** 5R34MH131914-02
- **Recipient organization:** UNIVERSITY OF ROCHESTER
- **Principal Investigator:** Jennifer Lockman
- **Activity code:** R34 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $279,613
- **Award type:** 5
- **Project period:** 2023-04-19 → 2026-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10830386

## Citation

> US National Institutes of Health, RePORTER application 10830386, Pilot Effectiveness Trial of THRIVE in Crisis Stabilization Centers: Promoting Connection, Recovery, and Treatment Linkage after Suicide Crisis (5R34MH131914-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10830386. Licensed CC0.

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