# Administrative Core

> **NIH NIH U2C** · HARVARD MEDICAL SCHOOL · 2024 · $1,129,119

## Abstract

PROJECT SUMMARY
Without access to a connected and streamlined process for diagnosis, research, and care, many patients with
rare conditions go from one institution to the next without a diagnosis or advancements in their care. In order to
address this problem, infrastructure and protocols to support the diagnostic process and generate knowledge
about underlying disease mechanisms were created as part of the Undiagnosed Diseases Network (UDN). The
Administrative Core of the Data Management Coordinating Center (DMCC) for Diagnostic Centers of
Excellence will advance infrastructure developed in the UDN and support novel methods to accelerate
diagnosis, research, and care for patients with undiagnosed conditions. The Administrative Core will be
responsible for uniting both the DMCC and broader Network. Development of partnerships will be crucial to the
Administrative Core in order to scale operations and ensure the Network is sustainable in the future. The
Administrative Core will organize its work around accomplishing the following three specific aims: 1) Drive and
advance DMCC and Network operations by providing scientific leadership and robust infrastructure, 2) Identify
and eliminate barriers to evaluation, diagnosis, research, and follow-up for patients with undiagnosed
conditions, and 3) Initiate and cultivate strategic partnerships and educational initiatives to expand network
impact.

## Key facts

- **NIH application ID:** 10830465
- **Project number:** 5U2CNS132415-02
- **Recipient organization:** HARVARD MEDICAL SCHOOL
- **Principal Investigator:** ISAAC S. KOHANE
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,129,119
- **Award type:** 5
- **Project period:** 2023-04-19 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10830465

## Citation

> US National Institutes of Health, RePORTER application 10830465, Administrative Core (5U2CNS132415-02). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10830465. Licensed CC0.

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