# Data Management Core

> **NIH NIH U2C** · HARVARD MEDICAL SCHOOL · 2024 · $1,422,378

## Abstract

PROJECT SUMMARY
To support diagnosis for a larger number of patients impacted by undiagnosed conditions, innovative software
solutions are needed to streamline and scale operations. The Data Management Core of the Data
Management Coordinating Center for Diagnostic Centers of Excellence will lead the design and
implementation of these solutions, creating platforms to support and scale patient enrollment, data collection,
and analysis. Having one central system will facilitate Network milestone and benchmark reporting as well as
identification and resolution of data submission and quality issues over time. The platform will support
collection and storage of multi-modal data data types and expand connectivity between clinicians, researchers,
and patients, leading to collaborative problem-solving and rapid adoption of novel pipelines. The Data
Management Core will focus on the following four specific aims as part of this project: 1) Scale up Network
capacity with automation, AI-based tier triage/escalation, and centralized expert analysis, 2) Implement a
two-way patient-facing portal to facilitate and enhance data collection and reporting as well as communication
between the patient, their clinician, and the diagnostic team, 3) Develop a team-based communication and
collaboration platform for effective analysis of network-level phenotype and genotype data, and 4) Integrate
and harmonize tools across the Network platform.

## Key facts

- **NIH application ID:** 10830466
- **Project number:** 5U2CNS132415-02
- **Recipient organization:** HARVARD MEDICAL SCHOOL
- **Principal Investigator:** Gabor T Marth
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,422,378
- **Award type:** 5
- **Project period:** 2023-04-19 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10830466

## Citation

> US National Institutes of Health, RePORTER application 10830466, Data Management Core (5U2CNS132415-02). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10830466. Licensed CC0.

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