# Case Comprehensive Cancer Center Support Grant

> **NIH NIH P30** · CASE WESTERN RESERVE UNIVERSITY · 2024 · $5,673,191

## Abstract

OVERALL
PROJECT SUMMARY/ABSTRACT
The mission of Case Comprehensive Cancer Center (Case CCC), now in its 27th grant year, is to promote a 
coordinated, translational research-oriented culture of scientific discovery applied to human cancers, that 
improves cancer detection, prevention, treatment, cure, and survivorship in Cleveland, Northeast Ohio and 
around the world, and to disseminate its advances to patients and populations. The Center provides leadership 
and oversight of collaboration for basic cancer research oriented toward identification of novel therapeutic 
targets; prevention, control and population research; therapeutic and non-therapeutic clinical research across 
the disease spectrum; and community outreach. These accomplishments include examples of practice 
changing impact within the catchment area and nationally. The Center coordinates all aspects of cancer 
research in Cleveland and Northern Ohio, including activities of the affiliate institutions of Case Western 
Reserve University, Cleveland Clinic, and University Hospitals. The Center provides opportunities to participate 
in clinical trials to almost 16,000 cancer patients (over 62% of cancer cases in the catchment area) who are 
newly diagnosed annually in the region. The Case CCC is organized around 7 Research Programs, 13 Shared 
Resources, and a clinical and behavioral cancer research infrastructure that prioritizes innovative translational 
research and investigator-initiated clinical trials that cut across the Research Programs. The Case CCC 
includes 279 members (172 Full, 32 Associate, and 75 Clinical) from 7 schools and 68 academic departments 
who actively participate in Center activities including Program and Shared Resource meetings and retreats, 
and leadership committees, each promoting a transdisciplinary approach that facilitates discovery and clinical 
application. The cancer focus of the Center is exceptional, with over $77M in direct funding and over $26M in 
direct NCI funding. Institutional commitment is also exceptional, codified through an updated Memorandum of 
Understanding. The consortium members will provide over $128M of internal funds for cancer research in the 
next grant cycle. The Case CCC and its affiliate institutions have established an outstanding infrastructure that 
enables its members to improve the prevention, diagnosis, and treatment of cancer through discovery, 
implementation and dissemination, and collaborative transdisciplinary research while providing state-of-the-art 
care and treatment to cancer patients and their families. The Case CCC yields tangible benefits as an active 
partner with the NCI by supporting cancer relevant scientific research with direct benefit to patients and the 
general public.

## Key facts

- **NIH application ID:** 10831549
- **Project number:** 5P30CA043703-34
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** GARY K SCHWARTZ
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $5,673,191
- **Award type:** 5
- **Project period:** 1997-08-01 → 2025-06-16

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10831549

## Citation

> US National Institutes of Health, RePORTER application 10831549, Case Comprehensive Cancer Center Support Grant (5P30CA043703-34). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10831549. Licensed CC0.

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