Abstract The overarching goal of this proposal is to help early career psychiatrist investigators (i.e., mentees) develop and maintain a research career path via our multi-component Research Colloquium for Junior Psychiatrist Investigators program (the Research Colloquium). The Research Colloquium aims to strengthen and diversify the psychiatrist-scientist workforce. It offers team-based and one-on-one mentorship and research career development to mentees in two tracks that differentiate participants’ current research experience (i.e., beginner and intermediate) across six core research areas including basic neuroscience and translational research, clinical psychobiology, health services/health disparities research, treatment and intervention research, alcohol, pain and other substance use research, and military and veteran mental health research. Each year, the Research Colloquium gives 40-50 early career psychiatrist investigators, a year-round, immersive research experience. This application seeks 5 years of support to facilitate the in-person components of the Research Colloquium specifically for the Alcohol, Pain, and Other Substance Use Research Area for the 2023 – 2028 cohorts. Each year, the funds from this award will partially support a cohort of 15 early research career psychiatrists with interest in Alcohol, Pain, and Other Substance Use research to attend the in-person components of the Research Colloquium, which include: 1) the initial 2-day Research Colloquium held contiguous to the APA Annual Meeting; 2) the 6-month follow-up Booster Session held contiguous to the American College of Neuropsychopharmacology (ACNP) Annual Meeting; and 3) the 12-month follow-up Booster Session held contiguous to the Society of Biological Psychiatry (SOBP) Annual Meeting. The specific aims are to: 1) identify current and future senior psychiatry residents, research fellows, and junior psychiatrists who are promising candidates for successful research careers in the mental health space; 2) assess the strengths, weakness, areas for improvement, and specific goals to be accomplished by mentees during their participation in the Research Colloquium; 3) provide a 2-day, intensive mentored training session that will allow mentees to present their current or proposed research protocols in small group and poster sessions and receive feedback for enhancements and guidance for future career progression; 4) provide a 1-day, intensive mentored 6-month follow-up booster session where mentees will present updates on their research and progress towards their goals for the program in small group sessions, discuss any barriers to their success, and receive guidance to facilitate progress; 5) provide a 1-day, intensive mentored 12-month follow- up booster session where mentees will present their final research projects in small group sessions and receive guidance on transition to the next step in their career development; 6) provide mentees with mentoring (i.e., from se...