# A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research

> **NIH NIH U24** · MEDICAL COLLEGE OF WISCONSIN · 2024 · $6,375,686

## Abstract

PROJECT SUMMARY/ABSTRACT
The Center for International Blood and Marrow Transplant Research (CIBMTR) is a clinical research program
dedicated to addressing important issues in the field of Hematopoietic Cell Transplantation (HCT) and Adoptive
Cell Therapy (ACT). CIBMTR maintains a large outcomes registry with information for >625,000 HCT/ACT
patients in treatment centers in the United States and internationally and provides statistical support and
scientific expertise for analyzing those data. A separately funded research repository of biospecimens linked to
these clinical data is available for a large subset of HCT recipients. CIBMTR recently began collecting patient-
reported outcomes (PROs), information collected directly from the patient to understand their experience of the
therapy and its impact on their quality of life and links these data to clinical outcomes. CIBMTR is dedicated to
supporting research to inform clinical practice for patients with cancer and non-malignant blood disorders. Use
of the registry by thousands of investigators around the world during the current and previous funding cycles
has contributed to >1,700 publications on important issues. This knowledge has been disseminated to multiple
stakeholders to speed innovation across our field and improve outcomes for our patients. CIBMTR will
continue to build on the infrastructure made possible by the support provided by the NIH, and in this application
proposes to enhance this registry and to advance its utility through the following specific aims:
Resource Development: To maintain and enhance the scope and broad usability of the registry by
adding new indications (e.g., solid tumors, infection) and data types (e.g., PROs) and optimizing the data
lifecycle.
Resource Utilization: To support novel research in hematological malignant and non-malignant
disorders and solid tumors, in a timely manner through observational research; correlative studies (e.g.,
biospecimens, PRO); supporting other data initiatives (especially federally funded) and clinical trial networks;
and building collaborative relationships.

## Key facts

- **NIH application ID:** 10833202
- **Project number:** 5U24CA076518-27
- **Recipient organization:** MEDICAL COLLEGE OF WISCONSIN
- **Principal Investigator:** Marcelo C. Pasquini
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $6,375,686
- **Award type:** 5
- **Project period:** 1998-03-01 → 2028-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10833202

## Citation

> US National Institutes of Health, RePORTER application 10833202, A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research (5U24CA076518-27). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10833202. Licensed CC0.

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