Project summary (Admin Core) The Administrative Core of the NYU BCC EDRN will provide leadership by establishing and maintaining the infrastructure, organization, coordination, and fiscal management necessary to successfully complete the tasks proposed within this application in the proposed timeframe, namely to develop and establish highly predictive biomarkers via a throughput approach that can be standardized into a CLIA level assay. The Administrative Core will ensure bidirectional exchange of findings and insights with other BCCs and CVCs, will work with the EDRN DMCC to provide logistical and organizational support needed for data integration, and ensure participation in collaborative projects with other laboratories and centers. In order to accomplish these general goals for this BCC application we will provide administrative support for NYU BCC EDRN activities (Aim 1), coordinate NYU BCC EDRN efforts integrating BDL with BRL (Aim 2) and facilitate evaluation and planning of NYU BCC EDRN activities (Aim 3). The administrative core will be led by Dr. Leopoldo Segal (contact PI of this application) and will include mPIs, Dr. Harvey Pass. In addition, the Admin core will designate Dr. Jun-Chieh (James) Tsay as NYU EDRN Administrator, and Ms. Lira Gutierrez, Administrative Assistant. The main focus of the Admin Core will include to provide fiscal management for the projects, prepare and file regulatory documents/progress reports, coordinate BDL-BRL interactions as well as interactions with the Perlmutter Cancer Center, monitor progress in each component of this BCC and identify new projects with translational impact as well as facilitate junior faculty development.