# Harnessing Innovation to Transform Malaria Surveillance into Key Interventions Across Transmission Settings in Zambia

> **NIH NIH U19** · JOHNS HOPKINS UNIVERSITY · 2024 · $754,100

## Abstract

ABSTRACT
The Southern and Central Africa International Center of Excellence for Malaria Research (ICEMR),
consisting of the Tropical Diseases Research Centre and Macha Research Trust in Zambia and the Johns
Hopkins Malaria Research Institute in the United States, has conducted innovative, applied research to
understand the epidemiology of malaria across diverse transmission settings. However, progress towards
malaria control and elimination has stalled across many countries in sub-Saharan Africa despite continued
and intensified investment, including in Zambia. Novel approaches are needed to better understand
epidemiological, entomological, and transmission patterns to strengthen malaria surveillance systems and
guide interventions and strategies. Longstanding studies like the ICEMRs provide a unique opportunity to
address outstanding scientific questions, explore novel data streams, and integrate research with
programmatic efforts to translate scientific knowledge into practice. In this third funding cycle of the ICEMRs,
we will leverage the deep understanding we have gained over the past 13 years to explore innovative data
streams, metrics, analytics, and surveillance tools to fill knowledge gaps, improve strategic decision-making,
and better equip the Zambian National Malaria Elimination Programme and local research institutions to
achieve the country’s malaria elimination goals across high, medium, and low transmission settings beyond
the duration of this ICEMR program. The theme of this ICEMR renewal application is to harness innovation to
transform malaria surveillance into key interventions, derived from the World Health Organization’s Global
Technical Strategy for Malaria 2016–2030. These innovative approaches will include the use of crowd-
sourced data, volatilomics, machine learning forecasting models, data visualization tools at small spatial
scales for local use, and periodic serological surveillance using residual blood specimens. By harnessing
innovation and exploring novel data streams, malaria metrics, analytical methods, surveillance tools, and
their applications to fill existing knowledge gaps and inform strategies, we hope to transform malaria
surveillance into key interventions in collaboration with the Zambian National Malaria Elimination
Programme, the President’s Malaria Initiative, and other partners to achieve national and regional malaria
control and elimination goals.

## Key facts

- **NIH application ID:** 10837336
- **Project number:** 2U19AI089680-15
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** WILLIAM J MOSS
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $754,100
- **Award type:** 2
- **Project period:** 2010-07-01 → 2029-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10837336

## Citation

> US National Institutes of Health, RePORTER application 10837336, Harnessing Innovation to Transform Malaria Surveillance into Key Interventions Across Transmission Settings in Zambia (2U19AI089680-15). Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/grant/nih/10837336. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*