Administrative Core Abstract The Administrative Core of the Southern and Central Africa International Centers of Excellence for Malaria Research (ICEMR) will build on the experience and successes of the prior ICEMR programs. Over the past 13 years the Administrative Core of the Southern Africa ICEMR established strong personal, management, and financial relationships with our partner institutions in Zambia - Macha Research Trust and the Tropical Diseases Research Centre. These relationships took years to develop and mature and will form the foundation for the Administrative Core of the Southern and Central Africa ICEMR. The Administrative Core will provide the leadership, guidance, administrative support, financial management and oversight to ensure the efficient resource management and success of the Southern and Central Africa ICEMR. This will be achieved in part by hosting weekly project meetings with all partners, coordinating meetings of the Scientific Advisory Group, participating in annual ICEMR meetings, and preparing reports. The Administrative Core’s mid- and short- term goals are to ensure that resources are managed efficiently and the planned research activities are coordinated, tracked, reported, and completed within the proposed timelines. The long-term goals of the Administrative Core are to ensure that the Southern and Central Africa ICEMR makes substantial contributions to regional malaria control and elimination through research and capacity building and the scope of work described for the two Research Areas and the Data Management and Analytics and Computational Modeling Cores.