# Shared Resource Management

> **NIH NIH P30** · UNIVERSITY OF COLORADO DENVER · 2024 · $1,383,017

## Abstract

ABSTRACT 
Shared Resource (SR) Management is under the direction of the Associate Director for Basic Research, Ford 
(THI), and is structured to ensure that the University of Colorado Cancer Center (UCCC) invests in cutting edge 
technologies and research services that advance the research efforts of UCCC members. In the last cycle, 
the CCSG supported 10 SRs. Twelve SRs are presented in this renewal representing new SRs, added services 
and technologies, and restructured SRs that are aligned with UCCC members' current research and are focused 
on developing and innovating services and processes, and adopting new technologies to help drive members' 
research forward. The roster of SRs includes Animal Imaging, Biostatistics and Bioinformatics, Cell 
Technologies, Drug Discovery and Development, Flow Cytometry, Functional Genomics, Genomics, Human 
Immune Monitoring, Mass Spectrometry, Pathology, Population Health, and Structural Biology. In addition, a 
Pre-clinical Human Immune System Mouse Models SR is under development to support UCCC member 
research in tumor immunology and novel immunology-based therapies. To ensure that UCCC SRs serve 
members optimally, input and evaluation is solicited from users, internal and external advisory groups, and 
institutional stakeholders to inform decisions made by the UCCC Executive Committee (EC) on investments in, 
and changes to, UCCC SRs including the allocation of CCSG and institutional support, capital investments, 
development of new SRs, and sunsetting outdated or underperforming SRs. Over the past funding period, capital 
and operational investments totaling $26.9M have enabled the acquisition of cutting edge technologies such as 
multiplexed immunostaining (Vectra/MIBI), a NovaSeq 6000, a 10x Genomics Chromium to support single cell 
sequencing efforts, and a 9.4 Tesla MRI for high resolution imaging; upgrades of NMR systems, IncuCytes, IVIS 
and CT scanners; multiple mass spectrometers; addition of equipment to drive efficiencies (e.g. Sony MA900 
self-run cell sorter; development of applications to support basic analyses of RNAseq data); replacement of aging 
equipment; and addition of services to drive member research forward (e.g. CryoEM for structural studies, 
organoid models for tumor biology studies, and high-throughput screening for drug discovery), while keeping all 
within reach of most funded investigators. Ninety-four percent (94% / n=247) of UCCC members have used the 
SRs over the funding period demonstrating the value of the SRs to members' research. Sixty percent (60%) of 
the UCCC users were peer-reviewed at the time of use. UCCC SRs contributed to 548 cancer-focused 
publications in the past cycle, many of which are high-profile as demonstrated by the fact that 21% have an 
impact factor (IF) ≥ 10 and that publications appear in journals such as Cell, Cancer Cell, and Nature Medicine. 
In short, UCCC SR Management is committed to ensuring each SR is providing essential, cutting ed...

## Key facts

- **NIH application ID:** 10838377
- **Project number:** 5P30CA046934-36
- **Recipient organization:** UNIVERSITY OF COLORADO DENVER
- **Principal Investigator:** RICHARD D SCHULICK
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,383,017
- **Award type:** 5
- **Project period:** 1997-04-04 → 2027-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10838377

## Citation

> US National Institutes of Health, RePORTER application 10838377, Shared Resource Management (5P30CA046934-36). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10838377. Licensed CC0.

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