# CNS-Met Administrative Core

> **NIH NIH P20** · UNIVERSITY OF KENTUCKY · 2024 · $936,807

## Abstract

PROJECT SUMMARY – ADMINISTRATIVE CORE 
 Research in CNS metabolism has garnered interest from many fields, including Alzheimer’s Disease, brain 
injury (including traumatic injury, stroke, etc), epilepsy, and Parkinson’s Disease, and likely involves all areas of 
CNS-related research. The University of Kentucky College of Medicine has made significant investments over 
the last few years in both metabolomics instrumentation and investigators with metabolomics expertise that 
enhanced existing UK strengths in neuroscience, cancer, cardiovascular, and diabetes & obesity research. The 
objective of this application is to create an NIH Center of Biomedical Research Excellence (COBRE) in CNS 
Metabolism (CNS-Met). This proposal builds on existing strengths at UK as well as strengths of both the senior 
and junior investigators in brain physiology, neuropathology, and CNS metabolism. The CNS-Met 
Administrative Core (Admin Core) will coordinate communication and access among the CNS-Met groups, the 
above-mentioned metabolism-centric research programs, and other existing UK strengths as well as core 
facilities established by other UK COBREs to support a multidisciplinary, team-based program that trains the 
next generation of faculty focused on brain metabolism. The CNS-Met Administrative Core is directed by Dr. 
Matthew Gentry and co-directed by Dr. Patrick Sullivan, senior scientists with complementary expertise in CNS 
metabolism and demonstrated leadership skills. The Core will ensure and provide effective coordination and 
oversight of research projects, research cores usage and service, general infrastructure, administrative, and 
fiscal matters. It will provide robust and timely financial management and will facilitate internal communication 
between CNS-Met constituents. It will be responsible for coordinating the recruitment of future research project 
leaders and mentors and for managing and implementing pilot program funding. The Admin Core will do all of 
these activities while ensuring that CNS-Met activities are in compliance with federal regulations. The 
overarching goal of the CNS-Met Administrative Core is to deliver administrative, fiscal, and scientific 
leadership and center-wide coordination to COBRE Research Project Leaders, their mentors, research 
core, and other COBRE-supported investigators. To achieve these goals, the core will: 1) Coordinate 
operational and fiscal management, infrastructure and program planning, and communication processes 
across all COBRE components.; and 2) Facilitate and coordinate research training, mentoring, and career 
development activities for early-stage investigators in brain metabolism research; 3) Implement a pilot studies 
program to seed new research across neuroscience research thrusts; and 4) Provide effective formative and 
summative assessment of COBRE projects and activities of the CNS-Met group.

## Key facts

- **NIH application ID:** 10841477
- **Project number:** 5P20GM148326-02
- **Recipient organization:** UNIVERSITY OF KENTUCKY
- **Principal Investigator:** Patrick G Sullivan
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $936,807
- **Award type:** 5
- **Project period:** 2023-05-15 → 2028-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10841477

## Citation

> US National Institutes of Health, RePORTER application 10841477, CNS-Met Administrative Core (5P20GM148326-02). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10841477. Licensed CC0.

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