7. PROJECT SUMMARY / ABSTRACT Coapt, LLC and Liberating Technologies, Inc, along with clinical collaborators at the Shirley Ryan AbilityLab, will systematically develop and evaluate a connected health system for data collected from upper limb prosthesis wearers using myoelectric control. The system will record wearer data relating to their daily prosthesis use and functional performance outside the clinic directly from the prosthesis hardware and through a mobile app which includes virtual game evaluation tasks. These data will be uploaded to our existing cloud storage platform, where cloud computing algorithms will analyze and highlight unique trends to provide the patient’s clinician with actionable insights that enable them to much more easily identify where to focus their therapeutic efforts in a user-friendly, web-based digital health portal, called the Clinician Dashboard. The objective of this effort is to improve the standard of care in upper limb prostheses by developing a commercially viable web portal which interfaces with Coapt’s existing state-of-the-art prosthesis controller, which is compatible with 400+ combinations of powered hand, wrist and elbow devices. This project builds on our preliminary development of a connected health system to (Aim 1) refine a web-based Clinician Dashboard prototype by adding cloud-based analysis of prosthesis use and performance data using an implementation science-informed design process, and (Aim 2) evaluate efficacy of the Clinician Dashboard in improving rehabilitation outcomes for new upper limb myoelectric prosthesis wearers. A formal participatory design process with key stakeholder (clinicians, patients, and technological experts) input, surveys, and usability assessments will be used to systematically inform the design and desired content of the Clinician Dashboard. We expect the Clinician Dashboard will assist clinicians in their clinical decision making for delivering more effective therapy which will, in turn, improve patient outcomes and accelerate their rehabilitation progress. The outcomes of this project will be results from a pilot clinical trial evaluating the efficacy of the Clinician Dashboard demonstrating improved rehabilitation outcomes which will support commercial deployment and marketing of our connected health system. This product will directly address an important clinician need that will be integrated into clinical practice to benefit the end-user - individuals with limb loss/absence who opt to use a myoelectric-controlled prosthesis. Our connected health system aims to improve functional outcomes and ability to complete activities of daily living (ADLs), increased prosthetic use and device satisfaction, and overall improved quality of life. Access to the Clinician Dashboard as part of a connected health system will be a distinctive feature of Coapt’s Complete Control system which we expect to also drive sales over our competitors.