# Core C

> **NIH NIH P01** · TEMPLE UNIV OF THE COMMONWEALTH · 2024 · $396,250

## Abstract

PROJECT SUMMARY
The Physiology and Surgical Core will provide the infrastructure to facilitate increased productivity and
synergy between the various projects to aid in defining the mechanisms by which exosomes mediate cell-to-
cell communication both within the heart, as well as cross-organ signaling, to regulate pathways involved in
cardiac injury and protection. The Core will not only provide a consistent and reproducible service in support
of the projects but will further participate in experimental design, prioritization of resources, and the
interpretation of data. In addition, Core C will identify additional areas for collaboration across all projects as
the program matures and thus be central to the interactive environment and comprehensive analysis of the
overall platform as data is generated. The core is a critical aspect to the success of the overall program
because it will provide dedicated and highly specialized services to all projects. Perhaps most importantly the
core will eliminate much of the noted variability in surgical techniques and protocol variations and thereby
enable a direct comparison of results across all projects.

## Key facts

- **NIH application ID:** 10844902
- **Project number:** 2P01HL134608-06A1
- **Recipient organization:** TEMPLE UNIV OF THE COMMONWEALTH
- **Principal Investigator:** John William Elrod
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $396,250
- **Award type:** 2
- **Project period:** 2017-09-01 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10844902

## Citation

> US National Institutes of Health, RePORTER application 10844902, Core C (2P01HL134608-06A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10844902. Licensed CC0.

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