# Bioinformatics Core Facility

> **NIH NIH P30** · UNIVERSITY OF CHICAGO · 2024 · $228,170

## Abstract

PROJECT SUMMARY/ABSTRACT - BIOINFORMATICS CORE FACILITY
The Bioinformatics Core Facility (BiCF) provides state-of-the-art bioinformatics expertise for the design,
analysis, and interpretation of genomics, proteomics, and other high-resolution, high-throughput studies to
better understand cancer biology and translate cancer -omics discoveries to cancer treatment for University
of Chicago Medicine Comprehensive Cancer Center (UCCCC) investigators. The objective of the BiCF is to
reduce the barrier for access to analytic expertise, maintain a high standard for data collection and
management, design and perform rigorous analytical strategies, and foster a collaborative and supportive
research community. BiCF provides expert bioinformatics support and services to carry out basic,
translational, clinical, and population science research, ensuring efficiency and high-quality analytic results.
In the reporting period, BiCF supported 39 unique UCCCC members (49% MMC, 8% CPC, 21% IC, 23%
CET), supporting their scientific needs and meeting the strategic objectives. During the funding period BiCF
supported 11 cancer-related federal grants, and 81 cancer relevant peer reviewed publications (51% in
journals with impact factor ≥ 10). Future efforts towards this end include: (i) expanding and creating new
pipelines to apply to other emerging genomics data including but not limited to single cell RNA-seq analysis,
single-cell mass cytometry and proteomics; (ii) developing novel bioinformatics tools to handle emerging
and diverse high-throughput data; (iii) collaborating with Genomics Core Facility (GCF) on a joint quarterly
educational program for UCCCC investigators on understanding and using data science to strengthen their
research; (iv) services for customized analysis beyond available standard pipelines on an as-needed basis.
Overall, BiCF is dedicated to pursuing a bold vision in the next funding period to facilitate cancer research
and provide cutting edge services that accelerate scientific progress.

## Key facts

- **NIH application ID:** 10845104
- **Project number:** 2P30CA014599-48
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **Principal Investigator:** Mengjie Chen
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $228,170
- **Award type:** 2
- **Project period:** 1997-09-01 → 2029-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10845104

## Citation

> US National Institutes of Health, RePORTER application 10845104, Bioinformatics Core Facility (2P30CA014599-48). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10845104. Licensed CC0.

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