# Biostatistics Core Facility

> **NIH NIH P30** · UNIVERSITY OF CHICAGO · 2024 · $280,045

## Abstract

PROJECT SUMMARY/ABSTRACT - BIOSTATISTICS CORE FACILITY (BCF)
The Biostatistics Core Facility (BCF) provides state-of-the-art statistical support for University of Chicago
Medicine Comprehensive Cancer Center (UCCCC) investigators engaged in clinical, translational, basic,
and population sciences research. BCF helps UCCCC investigators meet their scientific research objectives
by ensuring that studies are adequately powered, and that the data are appropriately analyzed and
interpreted. Careful consideration of sources of variation, bias, multiplicity issues, and potential confounding
factors is needed to reduce false positive (and false negative) findings. Appropriate study design also
reduces the occurrence of equivocal findings. Input into data collection and data management processes
can reduce errors, prevent or reduce the amount of missing data, and improve overall data quality. BCF
collaborates closely with UCCCC investigators to attain these goals. The services provided include: (i)
assistance with study design and data analysis plans; (ii) protocol development, randomization, and
statistical analysis for phase I, phase II, and phase III clinical trials; (iii) assistance in the design and analysis
of retrospective and prospective observational studies; (iv) analysis of genomic and other high-dimensional
data; (v) statistical analysis support for basic science and animal research projects. Advances in statistical
methodology related to cancer research is also an important goal. In the current CCSG cycle, BCF has
supported 86 unique UCCCC members, 82 clinical trials, 32 peer-reviewed cancer-related grants (78% NCI)
and 180 peer reviewed publications (28% in journals with impact factor ≥ 10).
In summary, the BCF is dedicated to providing UCCCC investigators with high-level statistical support to
facilitate cancer research and to meet the goals of the Strategic Plan.

## Key facts

- **NIH application ID:** 10845105
- **Project number:** 2P30CA014599-48
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **Principal Investigator:** Donald Hedeker
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $280,045
- **Award type:** 2
- **Project period:** 1997-09-01 → 2029-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10845105

## Citation

> US National Institutes of Health, RePORTER application 10845105, Biostatistics Core Facility (2P30CA014599-48). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10845105. Licensed CC0.

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