# Genomics Core

> **NIH NIH P01** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $407,759

## Abstract

SUMMARY
Single-cell/genomic technologies offer unprecedented opportunities to examine the cellular and molecular
mechanisms of disease initiation and progression, predict disease development and progression, and examine
how genetic and environmental risk factors mediate disease risk. Each of the four projects in this Program
leverages state-of-the-art genomic approaches aligned with the Project specific aims, which will be coordinated
and executed in close collaboration with the Genomics Core. This cross-institutional core will leverage
expertise in wet-lab single-cell methods, genetics, single-cell transcriptomics, epigenomic analyses, and lung
biology to provide integrated support for each Project. The Genomics Core will support all aspects of the
generation, storage, and computational analysis of single-cell and other genomic data through the studies in
Projects 1-4. The Genomics Core has four specific aims in support of its role: 1) to establish and implement
best-practices for generation of high-quality genomic data, 2) to facilitate secure storage and transfer of
genomic data across all Projects, 3) to provide best-practice-grounded analysis of transcriptomic and multiomic
data generated in Projects 1-4, and 4) to facilitate sharing and dissemination of genomic data and analysis
code. Through these aims, the Genomics Core will establish Standard Operating Procedures for each data
modality that will be generated across the Projects, serve as the genomic data storage/transfer hub in support
of each project, establish and deploy best-practice-based pipelines for key functions, and optimize purpose-
built analytic strategies for the specific research questions in the Projects. In addition, the Core will fulfill our
commitment to rapid and transparent data sharing by using approved portals to disseminate genomic data to
the research community.

## Key facts

- **NIH application ID:** 10846185
- **Project number:** 1P01HL172729-01
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** Nicholas Eli Banovich
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $407,759
- **Award type:** 1
- **Project period:** 2024-09-17 → 2029-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10846185

## Citation

> US National Institutes of Health, RePORTER application 10846185, Genomics Core (1P01HL172729-01). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10846185. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*