Project Summary This application is being submitted in response to the Notice of Special Interest (NOSI), NOT-CA-23- 038. The candidate, Oluseye Ajayi, is a Senior Science Officer and Prevention Advisor in a non - governmental organization, APIN Public Health Initiatives, in Nigeria. The goals of his application are to use the protected time provided through the program to (1) Build and strengthen mentoring relationships and skills transfer through regular interactions with mentors and co-mentors; (2) Acquire experiential skills in clinical epidemiologic research, and be able to translate this to public health practice (3) Conduct the rigorous research proposed in the application; (4) Acquire skills in epidemiological modeling, and artificial intelligence; (5) Establish research collaboration network and effectively coordinate multidisciplinary research projects, and (6) Be able to write, secure, and manage grants to conduct studies as well as write manuscripts for publication in high-impact journals. The proposed research titled “AVIVA-AI, Mentored Approach to Building Artificial Intelligence” is aimed at utilizing artificial intelligence (AI) matching strategy to design and integrate a client-oriented chatbot to an existing app "AVIVA" used in improving cervical cancer screening among women living with HIV (WLWH) in Nigeria. In AIM 1, we will design, deploy and integrate the chatbot into the AVIVA app using a multi-stage implementation model. In stage 1, we will gather WLWH questions and concerns about cervical screening and treatment over 3 months, through a deployed real-time social media platform- WhatsApp, manned by virtual support health care professionals (HCP). The questions and responses gathered from the social media platform will be used to build pre-defined information on an offline chatbot. In stage 2, the built chatbot will be deployed for real-time online utilization by the recipient of care (ROCs) and AI-matching of questions and concerns on a small scale, and the chatbot response appropriateness to ROCs questions will be assessed over 3 months by expert gynecologic-oncologist. In stage 3, the chatbot will be scaled up for utilization across HIV clinics in the two selected states. In AIM 2, we will conduct a brief assessment of WLWH Chatbot technology experience, behavioral intention to continue using the technology, and their perception of technology scalability among WLWH in HIV settings in Nigeria, while the full evaluation of the innovation (AIM 3) is proposed for implementation in future grant opportunities. This application builds on the candidate’s background experience and the expertise of his team of mentors and co-mentors in Nigeria and the US to achieve the training and research goals of this program. In the long term, the proposed research and training activities will provide the candidate with a unique set of experiential skills that will enable him to transition to independence as a scientist.