Summary: We propose to renew our 20-year-old UCI Training Program in Epilepsy Research which supports a total of four predoctoral and postdoctoral trainees. Epilepsy is the third most common brain disorder, and one that affects the young preferentially, with a tremendous loss of human potential. Surprisingly, Epilepsy is relatively understudied guide and develop the next cohorts of diverse, outstanding trainees and provide them with state- of the art conceptual, technical, quantitative and scientific rigor approaches to the understanding and underfunded; thus, there is a major unmet need to encourage and train the new generation of the Epilepsy Investigator Workforce. Our program has strived and succeeded in shepherding a robust and diverse cadre of pre- and postdoctoral trainees who are now engaging in Epilepsy and Neuroscience Research and Education, the majority in Academia and Industry. We now propose to of Epilepsy and its co-morbidities, as well as professional skills for their career development. Our progress to date and the current proposal demonstrate that we have the experience, environment, resources and passion to accomplish these goals.