ADMINISTRATIVE CORE: Abstract The Diabetes Research Center (DRC) of the Joslin Diabetes Center is a driving force in promoting scientific progress in the field of diabetes and related metabolic disorders at Joslin and in the surrounding Harvard Medical School (HMS) community. Funding for the DRC enables state-of-the-art Biomedical Research Core facilities, a Pilot & Feasibility Program that supports new and innovative research, and an Enrichment Program that serves as a stimulating platform for scientific exchange. These activities are organized and managed by the Administrative Core. Within this Core, the team of Director and Associate Directors brings a strong and informed vision of diabetes research. Together they develop, oversee, and integrate Center activities, with input from an engaged Internal Advsory Committee and external diabetes research experts who serve on the DRC External Advisory Committee. The Administrative Core serves a key role in coordinating Center activities with the administrative and scientific leadership at Joslin, Boston-area institutions, other DRCs, and the NIDDK. The broad and deep expertise of the Joslin DRC leadership team, combined with rigorous and regular self-assessments of the Center, enable the DRC to evolve Center activities nimbly to embrace new scientific advances and the development of new technologies.