Project Summary/Abstract This proposal is for a five-year continuation of the Harvard Medical School Research Fellowship Program in Integrative Medicine (IM). This three-year program prepares both clinician and non-clinician post-doctoral fellows for successful careers as academic research faculty and educators. The Harvard-wide program is based within the Division of General Medicine at Beth Israel Deaconess Medical Center with continued close collaboration with the Harvard Medical School (HMS) Osher Center for Integrative Medicine, an inter-institutional program that facilitates the development of research and education across Harvard in the growing field of complementary and integrative health (CIH) and whole person health. Our T32 training program has continued to evolve with the field and align with NCCIH strategic plan and goals. We have focused broadly on mind-body therapies (including mindfulness-based interventions, yoga, tai chi, and ‘placebo’ effects) that are long-standing areas of faculty expertise, as well as other areas within CIH such as chiropractic and acupuncture. Areas of more recent interest and expansion include nutrition and supplements, IM interface with technology, and a move towards implementation. Faculty mentors have funded research programs in IM/CIH research and impressive track records of successful mentoring. All trainees take part in the Program in Clinical Effectiveness, an intensive summer curriculum in epidemiology, biostatistics, and health services research at the Harvard T.H. Chan School of Public Health (HSPH). Some trainees continue at HSPH to earn a Master’s degree in Public Health during the first two years. Throughout the fellowship, weekly programs including seminars in research methodology/skills (e.g. study design, statistical considerations, grant writing) and a core program in evidence-based IM provides specialized clinical, research and scholarly skills in CIH. Fellows can also take in-depth courses in CIH in order to acquire practitioner skills/certification to inform their research. Most of the trainees’ time is devoted to mentored research, with careful matching of trainees with appropriate mentoring teams with relevant and specific expertise. Each trainee uses skills learned in the classroom to develop, conduct and analyze at least two original investigations under the direction of experienced faculty mentors. Research may span clinical trials, epidemiology, health services research, basic science and translational methodologies from bench to bedside. Fellows also participate in experiential retreats and have opportunities to teach IM at HMS. Fellows may further cultivate clinical skills in IM at one of several available integrative practice sites. Principal research mentors, clinical preceptors, and curriculum advisors supervise each fellow’s development. Over the first 23 years of the fellowship, 36 fellows have completed the program (38 in June 2023), 31 have earned an MPH, 22 have been awa...