# Developmental Research Program

> **NIH NIH P50** · SLOAN-KETTERING INST CAN RESEARCH · 2024 · $84,454

## Abstract

Developmental Research Program
ABSTRACT
The purpose of the Developmental Research Program of the MSK SPORE in Soft Tissue Sarcoma is to support
innovative translational research projects in sarcoma. The translational research projects in this program aim to
use knowledge of animal and human sarcoma biology to develop and test interventions related to improving
diagnosis, prognosis, and treatment of patients with soft tissue sarcoma. This program will allow us to respond
quickly to new opportunities in translational research and will help us recruit new scientific talent into our SPORE
and, more broadly, into sarcoma-relevant research. The specific aims of the Developmental Research Program
are: 1) to provide seed funding for innovative, investigator-initiated research in the biology, pathogenesis,
progression, and natural history of sarcoma, and 2) to fund research with exceptional potential to advance the
translational research goals of the SPORE. We are budgeting $400,000 yearly for this program including $50,000
from the SPORE award itself and $350,000 in MSK institutional and philanthropic funds (via the MSK Sarcoma
Center) to support at least two awards per year. The priority for funding will be those initiatives considered most
creative and of the highest scientific quality. Preference will be given to projects that complement the long-term
research goals of the SPORE and advance our translational research objectives. The executive committee may
also solicit and fund experimental or clinical proposals that address an urgent and specific need in the MSK
SPORE in Soft Tissue Sarcoma program or a unique research opportunity. We will prioritize projects submitted
by early-stage investigators and are committed to promoting diversity and strengthening the participation of
women and underrepresented groups in translational research. Applications will be reviewed by leaders at MSK,
including members of the Internal Scientific Advisory Board, selected based on the relevance of their scientific
expertise, and funding decisions will be made by the SPORE Executive Committee. The scientific progress of
DRP projects will be evaluated every six months by the DRP Co-leaders. Long-term metrics of success for DRP
awardees include presentation/publication of original research, successful competition for independent research
support, successful development and completion of clinical trials stemming from DRP research, establishment
of new collaborations, and institutional recognition by academic promotion. Projects may apply for a second year
of funding through the same competitive process, and the projects that appear most promising will be considered
for incorporation into the SPORE as Research Projects, either in current or future funding cycles.

## Key facts

- **NIH application ID:** 10848820
- **Project number:** 2P50CA217694-06A1
- **Recipient organization:** SLOAN-KETTERING INST CAN RESEARCH
- **Principal Investigator:** Marc Ladanyi
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $84,454
- **Award type:** 2
- **Project period:** 2018-09-01 → 2029-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10848820

## Citation

> US National Institutes of Health, RePORTER application 10848820, Developmental Research Program (2P50CA217694-06A1). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10848820. Licensed CC0.

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