The goal of this research education program ─ Inspiring Undergraduate Student Training in Alzheimer's Research (USTAR) ─ is to provide Black/African American (B/AA) undergraduate students with mentored didactic, clinical, and research experiences to stimulate interest in pursuing research careers related to Alzheimer's Disease and Related Dementias (ADRD). USTAR specifically focuses on social determinants of health as risk factors for ADRD in B/AAs. USTAR's scientific rationale is that B/AA undergraduates are less likely that White undergraduates to enter the biomedical workforce. This disparity is important because B/AAs are disproportionally affected by ADRD, and B/AA scientists may more deeply appreciate the sociocultural forces that create racial health disparities. USTAR brings together the research training skills of faculty at Thomas Jefferson University (TJU) and Delaware State University (DSU), a Historically Black College and University (HBCU). USTAR's multi-PI leaders include an ADRD clinical researcher (Rovner; TJU), a B/AA ADRD neuroscientist (Lawal; DSU), and a geriatrician who focuses on ADRD (Parks; TJU). Our combined expertise in ADRD research and clinical care, social determinants of health, neuroscience, neuroimaging, and interprofessional care in geriatrics, and our experience recruiting and mentoring B/AA undergraduates, guide this exciting new learning opportunity. The 20-month USTAR program will train two cohorts of ten rising junior B/AA undergraduates. Each USTAR trainee will have an Academic Mentor who advises on academic progress and career planning, and a Research Mentor who advises on research training. Trainees may seek optional mentorship from a B/AA faculty mentor if a trainee wishes to have a race-congruent mentoring experience. The USTAR program is comprised of: 1) two 8-week summer sessions (i.e., one session prior to both the junior and senior undergraduate years) that include didactic, research, clinical, and community-based learning experiences; 2) educational and research activities during the junior and senior academic years; and 3) a model longitudinal observational study of a racially diverse sample of older adults with normal cognition, mild cognitive impairment, and ADRD. Across all activities, we will emphasize the relationship between social determinants of health and cognition. Collaborating faculty include 17 clinicians and researchers with complementary expertise. The Specific Aims of USTAR are to: 1) Provide interdisciplinary ADRD-related research, educational, clinical, and community experiences; 2) Enhance trainee research skills via independent research projects; 3) Facilitate B/AA student transition from undergraduate to graduate studies in science; and 4) Evaluate USTAR's effectiveness. USTAR has potential to increase diversity in the national workforce that conducts health disparities research pertaining to ADRD. This goal aligns with the NIA mission to meet the nation's biomedical, behavior...