SURVEY, RECRUITMENT & BIOSPECIMEN COLLECTION SHARED RESOURCE: PROJECT SUMMARY The Georgetown Lombardi Comprehensive Cancer Center (LCCC) Survey, Recruitment & Biospecimen Collection Shared Resource (SRBSR) was established in July 2011 and has been CCSG supported since May 2014. The SRBSR is co-led by an oncology clinical research nurse administrator, Colleen McGuire RN, MSN, and a health services researcher, Arnold Potosky, PhD, MHS. The SRBSR provides LCCC Members with a comprehensive suite of services designed to meet their research needs, from consultative services prior to study initiation through survey development and implementation, database programming and preparation, subject recruitment and tracking, biospecimen acquisition, and data entry and data management. The SRBSR maintains and continuously updates a centralized, unified, and efficient patient registry (Georgetown MedStar Research Registry [GMR2]) and the Familial Cancer Registry (FCR) to facilitate subject recruitment and biospecimen acquisition for LCCC patients. Most (97%) subjects currently enrolled in this patient registry have consented to have their samples retained for future studies and to be contacted about future studies for which they may be eligible (96%). The SRBSR serves the needs of investigators from various disciplines, including behavioral scientists, clinical and translational researchers, epidemiologists, and basic scientists. The SRBSR receives input from the SRBSR Advisory Committee (AC) annually. In response to the prior critique to obtain more user feedback and to facilitate navigation of the SR, the SRBSR implemented three additional user surveys to prioritize development and assess programmatic needs, redesigned the SR webpage, and created an online request form to enhance navigation by prospective users. With respect to use, the SRBSR has enrolled 3,806 subjects into 19 studies in the current project period, including 5 clinical trials. During this time, the SRBSR collected 844 liquid and 64 tissue biospecimens. To ensure synergy with other Shared Resources, the SRBSR works closely with the Histopathology & Tissue Shared Resource and the Tissue Culture & Biobanking Shared Resource, which process and store the biospecimens. The SRBSR assists investigators in designing and implementing surveys based on robust and reliable data collection platforms. The SRBSR also validates, tracks and cleans datasets for analysis. The SRBSR has provided support for all three LCCC Research Programs. In FY2022, the SRBSR provided services to 24 LCCC Members across all three Research Programs (3 Cancer Cell Biology Members, 4 Cancer Host Interactions Members, and 17 Cancer Prevention and Control Members). In the recent project period, the impact of the SRBSR is demonstrated through the enabled success of 34 peer- reviewed publications, 5 clinical trials, and 39 extramurally funded research project grants for LCCC Members using SRBSR.