# Investigational Cancer Therapeutics Training Program (ICTTP)

> **NIH NIH T32** · SLOAN-KETTERING INST CAN RESEARCH · 2024 · $584,360

## Abstract

PROJECT SUMMARY/ABSTRACT
The goal of the T32 Investigational Cancer Therapeutics Training Program (ICTTP) at Memorial Sloan-
Kettering Cancer Center (MSK) is to provide highly select physician trainees in hematology and medical
oncology with the research training necessary for successful careers in the translation of cancer biology
discoveries into novel molecular, immune, or cell-based therapeutics, and those experimental treatments into
clinical trials that have the potential to change standards of care. The T32 ICTTP program accomplishes this
goal by combining a comprehensive mentored training program, an extensive didactic curriculum in clinical and
translational research methodologies, and experiential programs supporting development of the critical career
skills (e.g. collaboration, research management, grant writing) necessary for academic success. Each year, we
select 4 highly committed postdoctoral trainees from the pool of outstanding physicians at MSK who have
completed at least 3–4 years of both internal medicine and oncology/hematology clinical training. T32 trainees
are then supported for 2 consecutive years so that ≥ 80% of their time and effort is dedicated to research
training. Based on individual research interests and career goals, ICTTP trainees develop either a laboratory-
based or a prospective clinical research program with guidance from their mentors, who are established,
independently funded investigators. These programs involve extensive collaborative scientific interactions,
including additional clinical scientist mentorship for laboratory-based trainees and laboratory scientist
mentorship for clinical research trainees. The T32 ICTTP supplements mentored research training with a
curriculum of symposia, workshops, in-person didactic programs, and online courses that prepares trainees to
conduct successful, independently supported research at the faculty level. We continue to enhance the
program by revising and adding new educational programs in clinical research methodology, research ethics,
national and international clinical trial requirements and conduct, as well as hands-on writing workshops for
grants and protocols. Participating faculty mentors are continually reviewed and selected based on strict
criteria for research productivity, independent funding, and quality of mentoring. T32 ICTTP mentors have
research programs on cancer genetics, genomics, epigenetics, signal transduction, and metabolism; tumor
immunology and immunotherapy; drug and cellular therapeutic development; and tumor evolution, using
systems and computational approaches. Projects conducted by T32 ICTTP trainees in the proposed funding
period continue similar themes in cancer therapeutics research. All T32 ICTTP graduates from the last funding
cycle are continuing in faculty or pharmaceutical industry positions in cancer research, with the majority having
secured independent research funding. This success continues the ICTTP's 40-year track record...

## Key facts

- **NIH application ID:** 10849053
- **Project number:** 2T32CA009207-46
- **Recipient organization:** SLOAN-KETTERING INST CAN RESEARCH
- **Principal Investigator:** Omar Abdel-Wahab
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $584,360
- **Award type:** 2
- **Project period:** 1977-09-30 → 2029-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10849053

## Citation

> US National Institutes of Health, RePORTER application 10849053, Investigational Cancer Therapeutics Training Program (ICTTP) (2T32CA009207-46). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10849053. Licensed CC0.

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