This 5th competitive renewal application for an Institutional T32 training grant is made possible due to an outstanding base of aging research, funded mainly by the NIA at the Albert Einstein College of Medicine and Montefiore Health System. Included as the bedrock for this grant are the following programmatic features: Einstein Nathan Shock Center of Excellence in Basic Biology of Aging (E-NSC, an NIA-funded P30), the Paul Glenn Center for the Biology of Human Aging (E-Glenn), a hugely popular graduate course in the Biology of Aging developed specifically for this grant, a very successful hackathon that we instituted for the purposes of rigor and reproducibility training. Existing grant support for several aging research Programs (3 P01s and a U19) and significant growth in individual R01 awards show the success of our pool of training faculty. Einstein continues as a source of mentees, delivers collaborative environments, and fosters interactions with research gerontologists. Within this collaborative environment lies a strong emphasis in research on the biology of aging founded upon an accomplished group of well-funded mentors, who in turn have access to a strong pool of potential trainees. Our training program is built on successful and innovative programmatic and thematic areas of aging research. We are proud that 82.5% of our previous trainees from the past four training cycles continue in research-related endeavors, and the data tables in this proposal showing a continuing pool of highly-qualified eligible trainees. Our T32 program has been a success to date based on the quality of candidates, their scientific and academic achievements, and their enthusiasm for aging research. Because of our growth as an Aging Center, we are requesting to continue with three predoctoral and three predoctoral slots, as well as one flexible slot to strategically fill out our roster with the most exceptional candidates available, irrespective of pre- or postdoc status. We continue including MSTP students in our program, and their time to complete the PhD has remained consistent, showing the feasibility of their participation in our T32. With our responsive evaluation program in place, we have made changes such as increasing our co-mentoring program and adding a highly qualified Co-Director, Dr. Derek Huffman; shortening training periods for trainees who are not performing well to make the most of our investment; budgeting for a hackathon to follow up on the success of the previous ones, and maintaining the popular informal lunch meetings with the Director and Co-Director. Thus, our T32 predoctoral and postdoctoral training program continues to give participants state-of-the-art research training, exposure to leading investigators and fields of expertise in the biology of aging, enabling them to embark on successful careers involving research in aging and aging-related diseases.