# Training in the Neurobiology of Aging and Alzheimers Disease

> **NIH NIH T32** · UNIVERSITY OF CALIFORNIA-IRVINE · 2024 · $513,322

## Abstract

PROJECT SUMMARY/ABSTRACT
At present 6.7 million people in the US are living with Alzheimer’s disease and countless others are impacted
by age-related cognitive decline. The cost of care for these is skyrocketing. We urgently need to discover new
prevention and treatment strategies. To do this, we need to train the next generation of scientists in modern
techniques and in how to integrate findings across multiple domains and research approaches. UCI has a
long and distinguished history in the study of brain plasticity and learning and memory at multiple levels
and in integrating across levels and approaches. In addition, UCI has long and growing expertise in
neuroinflammation, stem cell biology and translational science, all of which are included in this training
program. However, new areas of strength have been developing and collaborations formed with enhanced
animal and human imaging, sleep researchers, cognitive sciences and clinical trials that is vital to real progress
in generating the capabilities to identify, treat and prevent/delay pathological decline in cognitive function. We
seek to provide pre- and postdoctoral trainees with training in concepts such as the integrative roles of
genetics and environment in brain aging and as a function of lifespan. Although a significant fraction of
research involves animal studies, we emphasize a broadened consideration of "bridging the gap" between
animal and human studies. Overall, our training program has six primary features and strengths: 1) A team of
innovative and scholarly preceptors who have a strong record of accomplishment for training young scholars;
2) An excellent collaborative environment; 3) A core set of courses on tailored to brain aging and dementia
research; 4) A set of seminars and symposia and training on brain pathology through Clinical-pathological case
presentations 5) Specific training in oral and written communication skills; and 6) Individual guidance and
mentoring to help trainees reach their career goals. Overall, our Training program in Neurobiology of Aging
and Alzheimer’s disease is designed to develop a uniquely trained cadre of investigators who over the years
will develop successful careers bench to clinic translation of research to improve the lives of the elderly and
ensure sustainably healthcare for the nation.

## Key facts

- **NIH application ID:** 10849493
- **Project number:** 2T32AG000096-41
- **Recipient organization:** UNIVERSITY OF CALIFORNIA-IRVINE
- **Principal Investigator:** Craig E Stark
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $513,322
- **Award type:** 2
- **Project period:** 1982-09-29 → 2029-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10849493

## Citation

> US National Institutes of Health, RePORTER application 10849493, Training in the Neurobiology of Aging and Alzheimers Disease (2T32AG000096-41). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10849493. Licensed CC0.

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