# Center for Lung Biology and Disease

> **NIH NIH P20** · LOUISIANA STATE UNIV A&M COL BATON ROUGE · 2024 · $2,178,191

## Abstract

SUMMARY
The Center for Lung Biology and Disease was established through a Phase I Centers of Biomedical
Research Excellence (COBRE) award. Our Phase I proposal, aimed at providing Promising Junior
Investigators (PJIs) an environment that maximizes their potential to contribute to advances in
pulmonary disease research, launched 6 new scientists in independent research careers funded through
11 R-, 1F- and 1K-series NIH grants. This Phase II proposal will expand the tremendously successful
programs established in Phase I, with an overarching goal of promoting research to unravel life-
threatening respiratory diseases. Its thematic focus encompasses mechanistic studies of host
responses to infectious and non-infectious stimuli. The leadership and mentoring teams are highly
interactive and our four new PJIs are a dynamic group. In aim 1 of our strategy to launch these PJIs as
independent researchers, we will maintain and expand an administrative structure that supports and fosters PJI
progress toward scientific independence. This will be accomplished by coordinating activities of the individual
projects and cores and fostering their collaborative engagement. We will also provide career and professional
resources that together with a team of mentors with strong experience in NIH-funded lung biology, will foster PJI
growth toward independent funding. In aim 2, we will enhance the research infrastructure at the LSU School of
Veterinary Medicine and provide cutting-edge technologies for enhancing the competitiveness of our PJIs.
Through partial funding from our Phase I award, we renovated and expanded our Animal Biosafety Level-2
(ABSL-2) footprint, and in this proposal, we will use institutional support to renovate and increase the footprint
of our ABSL-3 facility 2-3-fold. Given the landscape of junior investigator research within our LSU Vet Med
environment, where lung biology research emphasizes diseases induced by both infectious diseases and
inhalation exposures, we have realized the need for providing one new resource – the Inhalation and Infection
Core. The new core will assist investigators with animal infection and delivery of inhaled pollutants and/or
therapeutic agents to support their mechanistic studies of respiratory diseases induced through both infectious
and non-infectious stimuli. Finally, in aim 3, we will navigate pathways for sustained Center funding supported
through the NIH P01 grant program, with the ultimate goal of positioning our growing depth of lung biology
expertise to develop a Center of Excellence. The team assembled here has exceptional expertise in lung
biology, outstanding leadership and mentoring experience, and a demonstrated history of productive
collaboration. This COBRE program will provide novel insights into the pathogenesis of devastating lung
diseases to guide improved strategies for treating and preventing these diseases in human populations.

## Key facts

- **NIH application ID:** 10851551
- **Project number:** 2P20GM130555-06
- **Recipient organization:** LOUISIANA STATE UNIV A&M COL BATON ROUGE
- **Principal Investigator:** Stephania A Cormier
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $2,178,191
- **Award type:** 2
- **Project period:** 2019-01-02 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10851551

## Citation

> US National Institutes of Health, RePORTER application 10851551, Center for Lung Biology and Disease (2P20GM130555-06). Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/grant/nih/10851551. Licensed CC0.

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