# Molecular and Cell Biology Core (MCBC)

> **NIH NIH P20** · LOUISIANA STATE UNIV A&M COL BATON ROUGE · 2024 · $256,898

## Abstract

SUMMARY
The Molecular and Cell Biology Core (MCBC) of the Center for Lung Biology and Disease (CLBD) has been
created to meet the need for advanced molecular biology support by PJIs. The current application includes four
more JPI-led full projects that hold exceptional promise for being developed as independent investigators who
can compete nationally for categorial NIH funding. These projects require advanced molecular and cellular
biological principles, methods, and advances in genomics, transcriptomics, proteomics, immunology, and
microscopy to delineate fundamental cellular mechanisms leading to disease outcomes. In this Phase II renewal
application, the Molecular and Cell Biology Core (MCBC) proposes to continue to leverage, coordinate, and
expand the resources and expertise of the Division of Biotechnology and Molecular Medicine (BIOMMED) at
the LSU School of Veterinary Medicine. BIOMMED administers and coordinates access to specialized Core
Facilities, including the Gene Expression and Sequencing Laboratory (GeneLab), Viral Vectors Laboratory,
Protein Characterization and Purification Laboratory, which also generates monospecific and monoclonal
antibodies, and coordinates and facilitates access to a variety of other LSU Vet Med resources including the
LSU Vet Med Microscopy Center and the Shared Instrumentation Facility (main campus) which provides
advanced immunofluorescence and electron microscopy. MCBC offers biostatistics and advanced
bioinformatics analyses to analyze complex genomic and transcriptomic data to LSU and Louisiana researchers
in close collaboration with the LSU Center for Computation & Technology. MCBC aims to provide and
coordinate access to advanced instrumentation and services and develop and offer new molecular
methodologies. MCBC will also provide training for molecular biology and cell biology methodologies to all PJIs
and other NIH-funded investigators to achieve their research objectives. The MCBC has two specific aims: Aim
1. To provide the Center and other NIH-funded investigators with resources and expertise on advanced
molecular biology technologies, instrumentation, technical support, and development of molecular assays
needed for their projects. Aim 2. To organize, coordinate, and facilitate interactions among COBRE
investigators, mentors, and students; train PJIs and other faculty, staff, and students in advanced molecular
biology technologies; and establish long-term sustainability of all core services and functions. The MCBC
centralized molecular and cell biology services and training will provide outstanding capabilities in molecular
and cell biology methodologies. MCBC will streamline experimental tasks to maximize efficiency, productivity,
benefits, and efficient use of reagents, as well as assist PJIs in adopting and developing new technological
molecular and cell biology approaches.

## Key facts

- **NIH application ID:** 10851554
- **Project number:** 2P20GM130555-06
- **Recipient organization:** LOUISIANA STATE UNIV A&M COL BATON ROUGE
- **Principal Investigator:** Konstantin G Kousoulas
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $256,898
- **Award type:** 2
- **Project period:** 2019-01-02 → 2029-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10851554

## Citation

> US National Institutes of Health, RePORTER application 10851554, Molecular and Cell Biology Core (MCBC) (2P20GM130555-06). Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/grant/nih/10851554. Licensed CC0.

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