# Scientific Integration and Administration

> **NIH NIH P01** · UNIVERSITY OF ARIZONA · 2024 · $152,483

## Abstract

CORE A- Abstract
 The success of multidisciplinary, multi-investigator scientific programs critically depends not only on the
scientific quality of the individual research programs and their thematic synergy, but equally on the ability of the
group to work together and to stay on course to accomplish larger goals of the common endeavor. Even
greater scientific advancements are possible if teams can enhance the quality of science by cross-fertilization
of ideas and the potential to draw new conclusions from cross-analysis of data contributed by studying different
components of the same system (organism). Coordination of the above issues is particularly critical when the
area of research lies at an interface of two complex disciplines, as is clearly the case with research at the
interface of immunology and gerontology. All of the above necessitates a deliberate and systematic approach
to ensure Program success at all levels.
 To that effect, the Scientific Integration and Administration Core (Core A) will be the nerve center of the
Program, coordinating every aspect of its scientific and administrative progress. Specific Aims are to:
 SA1. Ensure scientific communication and exchange via: (i) regular monthly group videoconference
 meetings; (ii) a common and interactive experimental planning and data sharing space – the Thymus
 Rejuvenation PPG GoogleDoc platform and (iii) annual in-person PPG progress meetings. This Core will
 also organize and promote animal, tissue and reagent sharing via the above three means.
 SA2. Ensure fiscal and administrative oversight by monitoring spending with regard to specific aims
 and productivity of individual Projects and ensure timely annual reporting to the sponsor.
 SA3. Organize and implement scientific oversight. via (i) an internal PPG Scientific Steering Committee
 (PSSC), consisting of Project Leaders; and (ii) an external advisory board (EAB) composed of three
 scientists with strong expertise in the areas of the Program.
 SA 4. Provide coordinated data and knowledge sharing and management platforms (DKMP) to
 enable the distributed team members to securely share and harmonize data; to facilitate documentation of
 experimental progress and results; and to share laboratory protocols and analytic tools. This SA will
 oversee coordination of experimental data flowing to Core B that will be optimized via controlled
 ontologies, standardized meta-data collection, and common ID conventions to facilitate data mining, and
 cross-discovery between P1-P3. A Project Management Platform (PMP) utilizing GoogleDocs and Wiki
 technologies will facilitate inter-Project and Core interactions and delivery of Program goals under the
 guidance of the PSSC (see SA3). Of particular importance are the integration of single cell RNA-Seq data
 across projects, that will be integral for answering Program-level hypotheses.
This Core will therefore foster scientific integration at the highest level, while providing administrative c...

## Key facts

- **NIH application ID:** 10851679
- **Project number:** 5P01AG052359-07
- **Recipient organization:** UNIVERSITY OF ARIZONA
- **Principal Investigator:** JANKO Z. NIKOLICH
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $152,483
- **Award type:** 5
- **Project period:** 2017-09-15 → 2028-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10851679

## Citation

> US National Institutes of Health, RePORTER application 10851679, Scientific Integration and Administration (5P01AG052359-07). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10851679. Licensed CC0.

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