# Shared Instrumentation Grant application for EchoMRI whole body composition analyzer

> **NIH NIH S10** · OREGON HEALTH & SCIENCE UNIVERSITY · 2024 · $136,650

## Abstract

Abstract:
This proposal aims to secure funding for acquiring a new generation EchoMRI whole body
composition analyzer to address the urgent need for reliable and advanced research capabilities
that are critical to ensure uninterrupted progress and advance of federally funded projects at
OHSU. The new EchoMRI analyzer is capable of accurate measurements of whole-body
composition in small live animals, which is crucial for investigating metabolic disorders, monitoring
chronic disease progression and understanding disease mechanisms over time, especially in
young animals and during early development. The instrument currently available for OHSU
researchers is 16 years old, obsolete in both hardware and software, plagued by frequent and
unpredictable malfunctions, dwindling manufacturer support, and incompatible to upgrading. Its
increasingly frequent breakdowns have caused significant disruptions, delays and data loss in
NIH-funded studies. The requested new analyzer, with the latest versions of hardware and
software and enhanced capabilities,will not only solve the problemof unpredictableunavailability,
but will also offer expanded test modalities, new measurement capabilities, improved
measurement accuracy and enhanced data safety. It will be procured from the same vendor of
the instrument currently used at OHSU, EchoMRI LLC, which can ensure a seamless transition.
The new analyzer will cost $136,650 and will be managed by the OHSU University Shared
Resources (USR) program, providing access to at least nine NIH-funded research groups and
other OHSU affiliated institutions. With an optimized operation and management team in place,
acquisition of the new EchoMRI analyzer will empower researchers, facilitate breakthrough
discoveries, and contribute to solving critical health issues through investigations on metabolic
and endocrinological pathogenesis and pathophysiologic mechanisms of a broad range of chronic
diseases, of which comprehensive body composition analysis is often an indispensable and
critical part. This proposed investment holds great potential for transformative impacts on
research outcomes and the advancement of excellence in biomedical research.

## Key facts

- **NIH application ID:** 10852618
- **Project number:** 1S10OD034444-01A1
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** Zhenying Nie
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $136,650
- **Award type:** 1
- **Project period:** 2024-05-15 → 2026-05-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10852618

## Citation

> US National Institutes of Health, RePORTER application 10852618, Shared Instrumentation Grant application for EchoMRI whole body composition analyzer (1S10OD034444-01A1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10852618. Licensed CC0.

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