# Translational Coordination and Dissemination Center for the SCGE Consortium

> **NIH NIH U24** · MEDICAL COLLEGE OF WISCONSIN · 2024 · $1,752,114

## Abstract

PROJECT SUMMARY
The goal of the NIH Common Fund’s Somatic Cell Genome Editing (SCGE) program is to take
advances in technologies aimed at genome editing and delivery system approaches to correct
disease-causing mutations developed in Phase I and translate these efforts into the clinic during
Phase II. The SCGE Translational Coordination and Dissemination Center (TCDC) at the
Medical College of Wisconsin (MCW) will continue the efforts of the Phase I SCGE
Dissemination and Coordinating Center acting as the hub to support the three lab and clinical
trials-based initiatives in a coordinated effort to facilitate the dissemination of protocols, best
practices, SCGE results, and develop a network of collaboration. The SCGE TCDC at MCW
brings a team of experienced investigators, platforms for effective communication and tracking
of deliverables and milestones and demonstrated success in strategic collaborations within the
consortium. The overall goal for the SCGE TCDC is to support the SCGE Consortium and work
cooperatively with all initiatives, projects, and members to facilitate the objectives of the entire
SCGE Consortium. To accomplish this, the MCW TCDC will 1) build upon and extend the
current communication platforms to facilitate communication among participants, 2) develop the
infrastructure to collect, digest, annotate, integrate, and distribute data and resources generated
within the SCGE Consortium, and 3) create a robust platform for collaboration within the SCGE
Consortium and with outside partners. The MCW TCDC will create the infrastructure to develop
policies, track progress within the consortium, communicate within and beyond the consortium,
develop outreach and educational activities to support the process of moving pre-clinical studies
through the regulatory process, into clinical trials, and eventually to the patient. To disseminate
data and resources developed within the SCGE Consortium, the SCGE Platform will be
assembled to store, query, visualize, and analyze the outcomes of the SCGE initiatives. The
MCW TCDC team will facilitate the administrative and management activities to support the
overall success of the program.

## Key facts

- **NIH application ID:** 10852914
- **Project number:** 5U24HL168712-02
- **Recipient organization:** MEDICAL COLLEGE OF WISCONSIN
- **Principal Investigator:** MELINDA R DWINELL
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,752,114
- **Award type:** 5
- **Project period:** 2023-06-01 → 2028-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10852914

## Citation

> US National Institutes of Health, RePORTER application 10852914, Translational Coordination and Dissemination Center for the SCGE Consortium (5U24HL168712-02). Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/grant/nih/10852914. Licensed CC0.

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