# BD FACSDiscover S8 Image-Enabled Spectral Cell Sorter

> **NIH NIH S10** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2024 · $713,643

## Abstract

PROJECT SUMMARY/ABSTRACT
Funding is requested for the Becton Dickinson FACSDiscover S8, a high-end next-generation cell sorter with
unprecedented capabilities. The FACSDiscover S8 combines traditional high-speed electrostatic droplet
deflection technology with three novel features: real-time imaging, full-spectrum detection, and 6-way sorting.
With these unique capabilities, the FACSDiscover S8 can identify and purify up to 6 unique cell populations
based on morphology, spatial resolution of fluorescence signal, and spectrally unmixed fluorescence signals for
high-parameter measurements and subtraction of autofluorescence background for increased sensitivity. The
integration of the FACSDiscover S8 in the established and highly utilized Columbia Stem Cell Initiative (CSCI)
Flow Cytometry Core Facility at Columbia University Irving Medical Center (CUIMC) will provide Users across
the entire Columbia University campuses broad access to a currently unavailable technology that will vastly
expand the analytical capabilities and research opportunities of our scientific and medical community. The
FACSDiscover S8 will facilitate identification of unique cell populations with intricate granularity and will generate
deep insights into a broad array of human diseases investigated by the world-renowned researchers at Columbia
University, including in research areas such as stem cells, aging, neurodegeneration, cancer biology,
immunology, and bioengineering. The FACSDiscover S8 will therefore address an urgent and unmeet for our
Users and, given its cutting-edge technology, will also be a powerhouse for new discoveries for many years to
come.

## Key facts

- **NIH application ID:** 10853207
- **Project number:** 1S10OD036289-01
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Emmanuelle Passegue
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $713,643
- **Award type:** 1
- **Project period:** 2024-09-01 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10853207

## Citation

> US National Institutes of Health, RePORTER application 10853207, BD FACSDiscover S8 Image-Enabled Spectral Cell Sorter (1S10OD036289-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10853207. Licensed CC0.

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