# Cell sorting flow cytometer for BSL3 research

> **NIH NIH S10** · YALE UNIVERSITY · 2024 · $351,321

## Abstract

Project Summary
This shared instrument grant requests funds for a new flow cytometer, the Sony MA900, to be installed at
Yale University and dedicated to BSL3 research using fluorescence-based flow cytometry for either cell
sorting or purely analytic purposes. Flow Cytometry is a critical resource for biomedical research. Nearly
every discipline in the biologic sciences uses this technology that can be critical for a variety of
applications downstream of the sorting of cells based on phenotype. There is strong interest in studying
infectious disease at Yale – both at the cellular and host-response level. Many investigators performing
BSL3 research rely on a cell-sorting flow cytometer within the BSL3 facility to process infected cell
samples that can not undergo fixation. This is particularly important when cell sorting of unfixed infected
samples is required for subsequent in vitro cell culture assays or single cell RNA sequencing. Numerous
high-impact papers have resulted from prior BSL3 research at our institution, but many on-going studies
require continued access to reliable BSL3 flow cytometry. The requested equipment would replace an
aging BD FACSAria. The vendor will soon cease to offer service contracts on this model. Since this is the
only cell-sorting flow cytometer available for BSL3 researchers, any equipment breakdown could result in
delays that would significantly impede ongoing research. Thus, it is critical that this instrument be
replaced with a reliable cell-sorter that can be repaired in a timely fashion, preferably one that can be
operated independently by investigators when staff is not available.

## Key facts

- **NIH application ID:** 10853693
- **Project number:** 1S10OD036350-01
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** ANN M HABERMAN
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $351,321
- **Award type:** 1
- **Project period:** 2024-05-01 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10853693

## Citation

> US National Institutes of Health, RePORTER application 10853693, Cell sorting flow cytometer for BSL3 research (1S10OD036350-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10853693. Licensed CC0.

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