ABSTRACT The Technology and Data Management (TDM) Core serves two primary functions that are essential for the success of the EAS program project: (1) the management and integration of data, and (2) providing consultative and technical support for data operations. The aims of the TDM Core are as follow: Aim 1. To implement and oversee a central data repository and pipeline to facilitate the seamless exchange, integration and management of data among EAS Cores and Projects. Aim 2. To provide consultative and technical support to facilitate data collection and integration from different data sources (e.g., clinic, self-reports, wearable devices, sensors, biomarkers), and execute an operation plan for running and maintaining the central data infrastructure and management system. Aim 3. To score and evaluate basic psychometric properties (e.g., items and scores distributions, correlations, reliability) of clinical measures, conventional psychosocial scales and ambulatory assessments across Projects in order to provide tidy and analysis-ready datasets for further validation and analyses in the Statistical Core. Aim 4. To support and facilitate data dissemination and consortium collaborations with the scientific community and the public. In line with NIH Policy for data management and sharing (NOT-OD-21-013), and following the governance procedures distributed by the Dissemination Committee, the TDM Core will support the sharing of data, protocols, measurement and testing procedures, and relevant data dictionaries with the broader research community and lay public, by depositing data and metadata using various established repositories and platforms. The TDM Core follows the FAIR principles for scientific data management (Findable, Accessible, Interoperable, and Reusable), and will develop and operate a central data management and technical support system that will meet the scientific aims and research needs of the EAS P01, while also facilitating collaborations and dissemination with the broader research community and public.