# Cytation 5 Multimode Imaging System for UPR at Mayaguez Biomolecular Chemistry Facilities

> **NIH NIH S10** · UNIVERSITY OF PUERTO RICO MAYAGUEZ · 2024 · $244,901

## Abstract

Project Summary /Abstract
A multimode plate reader capable of live cell imaging would have a significant impact on the
biomedical research and educational community in the western and southern regions of Puerto
Rico. Four institutions would benefit from the acquisition of this technology, including the
University of Puerto Rico at Mayaguez, a resource-limited institution offering undergraduate and
graduate programs in biology, chemistry, and engineering. Among the major and minor users,
there are a total of four junior faculty members, and six different biomedical-related science
departments across the four institutions. The requested instrument is a Cytation 5 Imaging Multi-
mode Plate Reader, which includes a temperature/gas-controlled microscopic imaging reader,
multi-function capabilities for absorbance/fluorescence/luminescence readings, a plate stacker,
and an automated incubator. It is equipped with automated digital wide field microscopy and the
ability to link various detection modalities, imaging, and data analysis technologies into a compact,
user-friendly unit. This reader enables researchers to capture high-quality live cell images,
including 3D cultures, in real-time and various formats, offering advantages over traditional plate-
readers or microscopes. Acquiring this equipment would not only benefit the project team but also
other potential future users by allowing the capture of rich phenotypic information and meaningful
quantitative data on a single platform. This technology is crucial for establishing standard
operating procedures for high-throughput screening of bioactive compounds. Its utilization would
significantly advance research in understanding mechanisms and identifying new targets and
treatments for various diseases, while also contributing to the training of the next generation of
scientists. This proposal outlines how the requested equipment would be utilized to further
research in these areas and emphasizes the commitment of the University of Puerto Rico at
Mayagüez to oversee the administration and management of the instrument for the project team
and campus, ensuring its maintenance throughout its lifetime.

## Key facts

- **NIH application ID:** 10860445
- **Project number:** 1S10AG090400-01
- **Recipient organization:** UNIVERSITY OF PUERTO RICO MAYAGUEZ
- **Principal Investigator:** Jose A Carmona
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $244,901
- **Award type:** 1
- **Project period:** 2024-04-01 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10860445

## Citation

> US National Institutes of Health, RePORTER application 10860445, Cytation 5 Multimode Imaging System for UPR at Mayaguez Biomolecular Chemistry Facilities (1S10AG090400-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10860445. Licensed CC0.

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