Core A (Administrative Core) Summary The Administrative Core A (hereafter, Core A) will serve as the central entity to direct, oversee, and ensure the mission of the Flavivirus and Alphavirus ReVAMPP (FLARE) Center. The goal of Core A is to provide administrative support, financial and regulatory compliance, operational logistics, and scientific input and oversight of the research activities performed by the five Projects, the Data Management Core and the three Scientific Cores. Core A also will function to strengthen communication and data sharing within the FLARE Center, within the larger ReVAMPP network, and with other external stakeholders to ensure successful execution of the proposed aims in a highly collaborative environment. The following services, structured into two aims, will be provided by the Administrative Core A: (Aim 1) To provide overall grant management for the FLARE Center, such as budgetary support and fiscal oversight for the overall center; the nomination and establishment of a Scientific Advisory Board (SAB) and coordination of their activities; in collaboration with Project and Core Leaders, assurance of regulatory compliance as well as NIH required documentation; the development and implementation of measures to evaluate research progress of each Project and Scientific Core, as well as a conflict resolution plan. Moreover, Core A will support the publication of FLARE Center -derived manuscripts and administratively and financially support travel to the annual ReVAMPP Network-wide review meetings and mandatory ReVAMPP Center progress meetings. (Aim 2) To facilitate communication and collaboration within the FLARE Center as well as with external stakeholders to ensure a highly collaborative environment with timely information exchange. Specifically, Core A will promote regular communication and collaborations between Projects and Cores, including industry partners, as well as with the ReVAMPP Coordinating and Data Sharing Center (CDSC). Furthermore, Core A is committed to preparing the next generation of researchers for pandemic preparedness and, particularly, by supporting the mentoring and career advancement of trainees and faculty who are women or members of historically underrepresented or marginalized groups in science. In addition, Core A will maintain communication with the NIAID program officer(s) and other NIAID staff, coordinate reports to the NIH, and ensure compliance with NIH and local institutional requirements, as well as facilitate communication and support collaborative research activities with other ReVAMPP centers and outside collaborators.