ABSTRACT – Core A: Administrative Core The Administrative Core A of the Vaccines and Therapeutic Antibodies to Respirovirus, Rubulavirus, Peribunyavirus and Phenuivirus (R2P2) ReVAMPP Center serves as the communication and management control center of the R2P2 ReVAMPP Center. The main objective of this Core is to provide the necessary support structures for effectively managing, coordinating, and evaluating the Center's activities. The Core fulfills several critical functions: facilitating Go/No-Go decision making through quarterly evaluations of Projects and Cores, maintaining a Scientific Advisory Board (SAB) to review and recommend strategic changes, fostering collaboration and an interactive environment among Projects and Cores, and working with Project and Core leads to identify synergistic collaborations and additional resources. The leadership team composed of Sean Whelan, Anne Moscona, and Rino Rappuoli, along with the Associate Director, will form the senior management team of the Center, overseeing research progress, financial resources, and addressing challenges. The team will actively involve the Scientific Advisory Board, NIAID, and other stakeholders in decision-making processes. The Administrative Core will work with the Data Management Core to enhance collaboration by facilitating data sharing and integration. The Core will be instrumental for supporting interactions with the industrial partners, and creating a clear path from research to product development and will also ensure financial accountability and regulatory compliance, and monitor and evaluating the progress of research projects and Cores with the active involvement of the SAB, reporting progress to the SAB and NIAID through the preparation of annual progress reports. The Core will ensure that all Intellectual Property arrangements have been negotiated and completed prior to sharing and distribution of resources. The Core will act as a liaison between the Center and NIAID, coordinating visits between team members, SAB, and NIAID, managing publication submissions and covering publication costs and travel to ReVAMPP meetings, and establishing and maintaining a publicly accessible website summarizing the Center's activities. Overall, the Administrative Core plays a crucial role in facilitating effective decision-making, collaboration, compliance, and progress evaluation, ensuring the successful implementation of the ReVAMPP program. With an experienced leadership team and a well-defined structure, we are equipped to effectively fulfill these responsibilities and ensure the success of the R2P2- ReVAMPP goals.