# Outreach, Recruitment, and Education Core

> **NIH NIH P30** · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $537,312

## Abstract

ORE Core: Abstract
Research on Alzheimer Disease and Related Disorders (ADRD) has advanced significantly in recent years,
with the development of new knowledge and treatments across the ADRD continuum. But lack of education
about ADRD in the community contributes to ongoing fear and stigma such that those at risk or living with
ADRD often delay seeking care and are reluctant to participate in research, leading to knowledge gaps on the
meaning of clinical, fluid, and imaging biomarkers, and on the impact of pharmacological and other treatment
modalities on outcomes. Many clinicians also describe low levels of confidence around dementia diagnosis and
management, slowing referrals of persons to appropriate resources or research. These issues are particularly
marked among Black or African American (hereafter referred to as Black) and Hispanic groups, who are at 2-3-
fold higher risk for developing dementia than non-Hispanic Caucasian Americans yet remain underrepresented
in research studies. The MADRC Outreach, Recruitment and Engagement (ORE) Core will support the overall
theme of the MADRC - Understanding Drivers of Clinical Progression through: 1) working with each of the
Cores to further expand and diversify participation in ADRD clinical research, 2) acquiring new strategies to
find ways to bring research into the community; 3) further strengthening community partnerships, and 4)
training diverse clinicians, scientists, and research staff in community engaged research to increase dementia
knowledge and improve care. It will 1. Contribute to the MADRC’s ability to support and carry out clinical
research in ADRD by building, maintaining, and retaining our Research Cohort, working with partner
community organizations to increase understanding of dementia and dementia research participation, and
disseminating effective recruitment, engagement, and retention strategies; 2: Develop, in partnership with the
Clinical, Neuropath, Biomarkers, Data and Imaging Cores, new tools and strategies to bring educational
materials and research into the community; 3. Train the next generation in the science of community-engaged
research and in identification of at-risk persons or those living with dementia and provision of diagnostic
disclosure, and anticipatory guidance based on growing understanding of drivers of disease progression in
high-risk communities and minority populations; and 4: Increase the diversity of staff and research
participants so that studies are representative of the spectrum of race, ethnicity, gender identity, and ability
characterizing our community. We will harness input from our Community Advisory Board and other community
partners to both recruit and effectively retain participants from diverse backgrounds.

## Key facts

- **NIH application ID:** 10864399
- **Project number:** 2P30AG062421-06
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** Christine S Ritchie
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $537,312
- **Award type:** 2
- **Project period:** 2019-05-15 → 2029-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10864399

## Citation

> US National Institutes of Health, RePORTER application 10864399, Outreach, Recruitment, and Education Core (2P30AG062421-06). Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/grant/nih/10864399. Licensed CC0.

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