# Imaging and Response Assessment Core

> **NIH NIH P30** · WASHINGTON UNIVERSITY · 2024 · $313,852

## Abstract

IMAGING AND RESPONSE ASSESSMENT CORE (IRAC) SHARED RESOURCE: PROJECT SUMMARY
The Imaging and Response Assessment Core (IRAC) is a shared resource (SR) operated by the Department of
Radiology within the Washington University School of Medicine (WUSM). The IRAC facilitates research by
providing support services and analysis for both standard and novel imaging methods used for characterizing
tumor biology and predicting and monitoring response to therapy in patients enrolled in clinical trials performed
at the Siteman Cancer Center (SCC). To accomplish this, the IRAC provides a variety of services to investigators
including: 1) assistance with protocol development; 2) imaging-related regulatory services; 3) site qualification;
4) coordination of imaging examinations to ensure protocol compliance; 5) data transfer to trial sponsors or
external core laboratories; and 6) tumor measurements on both anatomical and functional imaging studies
performed by dedicated radiologists and nuclear medicine physicians. Additionally, the IRAC implements new
software tools to improve the accuracy and reproducibility of tumor measurements and to allow for incorporation
of newer approaches of tumor measurement (for example, three-dimensional volumetric measurements and
metabolic tumor volume) into clinical trials at SCC.
 The overall goal of IRAC is to increase the impact that quantitative imaging plays in clinical cancer research.
The IRAC provides unique imaging management and analysis services that are not available elsewhere within
the WUSM. The SCC has a large portfolio of clinical trials that use computed tomography (CT), magnetic
resonance imaging (MRI) and positron emission tomography (PET), and the IRAC contributes to the overall
success of SCC trials by providing these imaging support services to investigators.

## Key facts

- **NIH application ID:** 10866455
- **Project number:** 5P30CA091842-23
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** TIMOTHY J. EBERLEIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $313,852
- **Award type:** 5
- **Project period:** 2001-08-02 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10866455

## Citation

> US National Institutes of Health, RePORTER application 10866455, Imaging and Response Assessment Core (5P30CA091842-23). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10866455. Licensed CC0.

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