# Cancer Metabolomics and Proteomics

> **NIH NIH P30** · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $39,393

## Abstract

PROJECT SUMMARY
Mass spectrometry (MS) is the premier technology for detecting and quantifying metabolites, lipids, and proteins.
The mission of the University of Wisconsin Carbone Cancer Center (UWCCC) Cancer Metabolomics and
Proteomics (CAMP) resource is to facilitate access to cutting-edge MS data to support UWCCC investigators’
research. CAMP is led by MS expert Dr. Josh Coon (GEM), Professor and Director of an NIH Biotechnology
Research Center for MS technology development (P41GM108538); it encompasses the vibrant UW-Madison
MS community that includes 11 faculty expert laboratories and four MS core facilities. This community houses
and operates over 50 MS systems capable of targeted metabolite analysis up to exotic protein post-translational
modification (PTM) discovery and quantification. Since 2017, this collective group contributed to 106 UWCCC
user publications. UWCCC members wishing to incorporate MS into their research initially meet with CAMP
leadership to discuss project background, goals, timelines, etc. The consultation meeting(s) aim to provide
guidance and advice on experimental design, e.g., for an upcoming grant submission, and enough understanding
for the CAMP leadership to assess and match the project to the appropriate CAMP Expert MS lab or core facility.
Note CAMP’s expert leaders are personally involved in educating and facilitating the MS technology needs of
UWCCC members, helping them successfully navigate a complicated technology terrain. CAMP uses a
collaborative model where MS projects are covered jointly by CAMP network labs and UWCCC members. For
example, when a UWCCC CAMP project is conducted with the NIH P41 Center led by Coon and Li (TM), the
MS cost is incurred by that mechanism. In cases where the UWCCC member project is a better fit for a CAMP
core laboratory, the UWCCC member must identify funds for that work; however, CAMP will assist the member
with technical review of funding proposals and similar support, as needed. Further, to kickstart small projects
(either collaborative or through MS cores) we have established a microgrant program. CAMP is a UWCCC-
specific resource that provides all UWCCC members a fast-tracked structure through which to get expedited
guidance and access to cutting-edge MS. Specific aims are to 1) disseminate and inform UWCCC members on
the capabilities and utility of state-of-the-art MS technologies for cancer research; 2) consult and guide UWCCC
members on design and implementation of MS-based cancer research; and 3) connect UWCCC members with
the appropriate MS expert laboratory to expedite MS-based research and discovery. Over 2017-2021 as a
developing core CAMP has had tremendous impact on UWCCC member research. Specifically, CAMP
collaborated with 22 UWCCC program members across five scientific programs, which resulted in 22 cancer-
relevant peer-reviewed publications. With the recent expansion of CAMP’s expert network, we anticipate even
greater impact. Collectively since 2017...

## Key facts

- **NIH application ID:** 10873082
- **Project number:** 5P30CA014520-50
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **Principal Investigator:** Joshua J Coon
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $39,393
- **Award type:** 5
- **Project period:** 1997-04-25 → 2028-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10873082

## Citation

> US National Institutes of Health, RePORTER application 10873082, Cancer Metabolomics and Proteomics (5P30CA014520-50). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10873082. Licensed CC0.

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