# Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for Persons Giving Care or Living with AD/ADRD

> **NIH NIH P30** · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · 2024 · $1,271,724

## Abstract

PROJECT ABSTRACT
The goal of this Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for
Persons Giving Care or Living with AD/ADRD is to generate behavioral intervention development research
for enhancing physical activity (Roybal Theme: Spur the Initiation and Maintenance of Physical Activity
Regimens that are Personalized to Caregivers or Persons with AD/ADRD). The Northwell Roybal Center is
comprised of two components: the Administrative Core and the Behavioral Intervention Development Core.
Our Administrative Core will develop and provide the strategic vision, leadership, and the full range of NIH
Stage Model expertise needed for the success of this Roybal Center; monitor Center clinical trials progress
and provide immediate feedback; develop, identify, and use common metrics for Center productivity evaluation
purposes. Finally, the core will facilitate collaboration with other Roybal Centers, the Coordinating Center, the
National Institute on Aging, and scientists across the nation interested in advancing the initiation and
maintenance of physical activity regimens personalized to care providers or those living with AD/ADRD.
Our Behavioral Intervention Development (BID) Core will proactively determine a national pool of potential
eligible scientists for later national competitions, review and select meritorious clinical trials for funding, and
ensure compliance of all clinical trials with all regulatory agencies. The BID will then support investigators
identified via this national competition to implement identified innovative clinical trials that align with the themes
of the Northwell Roybal Center in Years 3 through 5 of the proposed project. The BID Core will also support
the conduct of two Stage II fully-powered clinical trials in Years 1 and 2 that aim to foster habitual physical
among caregivers for persons with AD/ADRD. Trial #1 will work to develop habitual daily walking among
caregivers. In contrast, Trial #2 will develop habitual hourly walking to reduce the amount of time caregivers
spend sedentary. Both trials will measure the key mechanism of behavior (MoBC) of cognitive automaticity.
The overall mission of the Northwell Roybal Center for Personalized Trials is to establish an infrastructure
organized per the NIH Stage Model with scientific expertise and resources to conduct Stages 0-V trials of the
translational behavioral intervention development pipeline, as well as examining key MoBCs of behavior
change, and so serve as a national resource for the behavioral and social intervention research community in
initiating and maintaining personalized physical activity regimen for caregivers or persons living with
AD/ADRD.

## Key facts

- **NIH application ID:** 10874250
- **Project number:** 2P30AG063786-05
- **Recipient organization:** FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
- **Principal Investigator:** Karina W. Davidson
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2024
- **Award amount:** $1,271,724
- **Award type:** 2
- **Project period:** 2020-08-15 → 2029-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10874250

## Citation

> US National Institutes of Health, RePORTER application 10874250, Northwell Roybal Center for Personalized Trials: Physical Activity Promotion for Persons Giving Care or Living with AD/ADRD (2P30AG063786-05). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10874250. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*